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Moumoujus

QUEEN BEE LARVA.

Valuable / SKIN CONDITIONING

Queen Bee Larva, also known as Apis Mellifera Larva Extract, is a nutrient-rich ingredient abundant in proteins, amino acids, fatty acids, and minerals. It primarily functions as a potent skin conditioning agent, enhancing texture, promoting softness, and maintaining a healthy, moisturized complexion. This extract also exhibits significant anti-aging, anti-inflammatory, and antioxidant properties.

Summary

Skin Conditioning Antioxidant Anti-aging Anti-inflammatory Collagenase Inhibitor Hyaluronidase Inhibitor Elasticity Enhancer Moisturizer Wound Healing

Science

Mechanism of Action

Queen Bee Larva (QBL) delivers its multifaceted benefits through its rich bio-composition, including proteins, amino acids, fatty acids, and minerals. It acts as a primary skin conditioning agent, improving skin texture and softness, while contributing to overall hydration. QBL's crude proteins and hydrolysates demonstrate robust antioxidant activity by scavenging free radicals and effectively inhibit collagenase, thereby preserving vital collagen integrity. Furthermore, it may contribute to the maintenance of extracellular matrix health through hyaluronidase inhibition. Alcohol extracts of QBL also provide liposoluble vitamins (A, D, E) which enhance skin elasticity, stimulate collagen formation, mitigate UV damage, support wound healing, and offer additional anti-inflammatory and moisturizing effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Crude proteins and hydrolysates demonstrated strong antioxidant and collagenase-inhibitory activities, without inducing skin irritation in HET-CAM tests.
  2. 02 A QBL-formulated cream exhibited 88.66% DPPH radical scavenging activity, which is comparable to 0.1 mg/mL vitamin C.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While generally uncommon, potential side effects include localized allergic reactions such as redness, itching, or swelling, and skin irritation, particularly in individuals with sensitive skin, or in rare cases, contact dermatitis. Patch testing is recommended prior to widespread application. Notably, a QBL protein extract at a concentration of 10 mg/mL did not induce skin irritation in HET-CAM tests. Oral toxicity studies in mice with freeze-dried QBL powder up to 5 g/kg/day showed no treatment-related mortality or systemic toxicity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Queen Bee Larva is a valuable ingredient, demonstrating significant antioxidant and anti-aging efficacy by inhibiting collagenase and enhancing skin texture, with a low risk of irritation across various skin types.

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References

Sources