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QUATERNIUM-53.

Insufficient Data CAS 68410-69-5 / ANTISTATIC, HAIR CONDITIONING

Quaternium-53, also known as Polyquaternium-53, is a cationic polymer primarily recognized for its conditioning capabilities in hair and nail care. It functions by interacting with negatively charged surfaces to impart smoothness and manageability.

hair conditioning film-forming agent fixing agent antistatic agent

Science

Quaternium-53 operates as a cationic polymer, forming an electrostatic bond with the anionic surface of hair strands. This interaction effectively smooths the hair cuticle, which reduces friction and leads to improved wet and dry detangling, enhanced shine, frizz control, and a reduction in static electricity. It further aids in film-forming and color retention for treated hair. While its mechanism is well-documented for hair and nails, specific mechanisms detailing its direct action or benefits on the skin itself are not extensively outlined in the provided research data.


Research

Medium confidence
Effective range 0.5–3%
Optimal

N/A

Key findings

  1. 01 Typical usage levels ranging from 0.5% to 3% in rinse-off conditioners and serums are associated with significant conditioning benefits, including improved detangling (both wet and dry), frizz control, enhanced shine, increased manageability, and improved color retention.

Transparency

Not commonly dusted

The provided research data does not indicate any concerns or information regarding 'dusting' for Quaternium-53.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Quaternium-53 generally exhibits good stability but can be susceptible to oxidation under certain conditions.

Conflicts

  • Formulation with high concentrations of anionic surfactants, such as Sodium Lauryl Sulfate (SLS) or certain soaps, may result in incompatibility. This can lead to precipitation or a reduction in the ingredient's functional efficacy, necessitating rigorous compatibility testing.

Safety

CIR Status
Safe with restrictions
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Quaternium-53 is safe for use in cosmetics when formulated to be non-irritating and utilized within current practices and concentrations. The EU's Scientific Committee on Consumer Safety (SCCS) has also approved its use, subject to restrictions detailed in Annex III of the EC Cosmetics Regulation. These restrictions may govern purity criteria, maximum concentration, or specific product categories. A universal maximum concentration is not provided, as it is contingent on these regulatory qualifications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While demonstrating robust efficacy in hair and nail conditioning, the available data for Quaternium-53 is insufficient to establish specific mechanisms or precision benefits for skin in a targeted skincare application.


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