Science
Mechanism of Action
As a cationic polymer, Quaternium-43 electrostatically adsorbs onto the negatively charged surfaces of the skin, forming a subtle, protective film. This film-forming action contributes to a smoother and softer skin texture and functions as a moisturizer by attracting and retaining humidity to prevent dryness. Additionally, it can act as a carrier, potentially influencing the penetration or retention of other active ingredients on the skin's surface.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
Quaternium-43 is not typically associated with 'dusting' in formulations; its role is functional rather than purely cosmetic marketing.
The Formula
Formulation
Stability
Polyquaterniums, including Quaternium-43, generally exhibit robust stability in formulations. Their water-soluble nature ensures even dispersion and complete dissolution, allowing for high concentrations while maintaining product integrity.
Conflicts
- Anionic polymers of surfactants (potential for complex formation and undesirable film, particularly in certain 2-in-1 shampoo formulations)
Safety
Safety Profile
Quaternium-43 is approved and subject to restrictions under Annex III of the EC Cosmetics Regulation, following an assessment by the SCCS, confirming its safe use under specified conditions. While a specific maximum concentration isn't provided, 'Cosmetic Restrictions: III/66' are noted. The Environmental Working Group (EWG) indicates low concerns for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity, but highlights a 'HIGH' concern regarding 'Use Restrictions'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Quaternium-43 is a valuable film-forming polymer that enhances skin smoothness, softness, and hydration, serving as an effective conditioning and moisturizing agent in formulations.
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References
Sources