Science
Mechanism of Action
As a quaternary ammonium compound, Quaternium-18 Methosulfate possesses a positive charge, allowing it to electrostatically bind to the negatively charged surfaces inherent in skin and hair. This interaction enables its diverse functions, including conditioning, acting as a surfactant, emulsifying immiscible phases, suspending particulates, and regulating product viscosity. Its emulsifying capacity specifically stabilizes oil-in-water formulations, preventing component separation.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The compound demonstrates optimal pH stability within the range of 4.0 to 6.0. As an emulsifier, it actively stabilizes oil-in-water formulations, which is critical for preventing component separation and maintaining product integrity.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that related compounds, Quaternium-18, Quaternium-18 Bentonite, and Quaternium-18 Hectorite, are safe for use in cosmetics. This finding was reaffirmed in 2003 and 2019, with the latter clarification noting no inhalation toxicity concerns for Quaternium-18 due to its large particle size. However, specific maximum concentration data for Quaternium-18 Methosulfate itself were not explicitly provided in the available CIR tables.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Quaternium-18 Methosulfate is a CIR-deemed safe, multi-functional ingredient providing formulation stability and conditioning benefits, although specific skin efficacy and compatibility data for this exact compound are currently limited.
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References
Sources