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Moumoujus

QUATERNIUM-16.

Optional CAS 64425-88-3 / 35239-12-4 / ANTISTATIC, HAIR CONDITIONING

Polyquaternium-16 is a synthetic, positively charged polymer designed to adhere to negatively charged skin and hair surfaces. It functions primarily as a conditioning agent, imparting a silky-smooth texture to the skin. Notably, it also demonstrates efficacy in reducing axillary bacteria and associated malodor.

Summary

Conditioning Agent Film-Forming Antistatic Deodorizing

Science

Mechanism of Action

As a cationic polymer, Polyquaternium-16 operates by electrostatically binding to the anionic surfaces prevalent on the skin. This interaction facilitates the formation of a conditioning film, which contributes to a refined, smooth skin texture and improves formulation adhesion. In specific applications, its bacteriostatic properties effectively decrease surface microbial populations.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A Polyquaternium-16-containing deodorant roll-on formulation significantly reduced axillary malodor and bacterial counts over 24 to 48 hours post-treatment. The formulation was well-tolerated and identified as an effective, skin-friendly active for deodorant applications.

Transparency

Dusting Analysis

Not commonly dusted

While not typically associated with powdery residue or 'dusting', high concentrations or prolonged application of Polyquaternium-16 may lead to product accumulation on the skin or hair, potentially resulting in a heavy or greasy sensation.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Polyquaternium-16 exhibits robust stability across a wide range of pH levels and temperatures. Its film-forming capabilities can protect encapsulated active components, thereby enhancing their stability, homogeneity, and uniform distribution within the final product.

Conflicts

  • strong bases
  • acids
  • oxygenizers

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Unknown

Polyquaternium-16 is generally considered safe for cosmetic applications when formulated within established guidelines. Although a specific CIR final report for Polyquaternium-16 was not found, related polyquaternium ingredients (e.g., Polyquaternium-6, -22, -39) have been reviewed and deemed safe. It is not listed on EWG's Skin Deep Restricted or Unacceptable Lists, and no specific SCCS opinion or FDA approval as a direct cosmetic ingredient was identified.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Polyquaternium-16 is a synthetic conditioning polymer offering a smooth skin feel and film-forming benefits, with demonstrated efficacy in reducing axillary bacteria in specific formulations.

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