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Moumoujus

QUASSIA AMARA WOOD.

Valuable CAS 84604-10-4 / SKIN CONDITIONING

Derived from the bark of the Quassia amara tree, this botanical extract is a powerful multi-tasker for compromised skin. It effectively addresses concerns ranging from inflammatory conditions like rosacea and seborrheic dermatitis to blemish-prone skin, leveraging its antimicrobial and soothing properties.

Summary

skin conditioning antimicrobial anti-inflammatory antioxidant astringent exfoliating sebum regulating collagen boosting tonic denaturant

Science

Mechanism of Action

Quassia amara wood extract operates through a multi-faceted approach to improve skin health. It exhibits significant antibacterial activity, targeting common skin pathogens such as P. acnes and Staphylococcus coagulase positive. Its potent anti-inflammatory action calms irritation, reduces redness, and alleviates swelling. Rich in antioxidants like flavonoids, it protects skin cells from oxidative stress. Additionally, it offers astringent and skin-conditioning benefits, aids in gentle exfoliation, helps regulate sebum production, and demonstrates antiparasitic efficacy against Demodex spp., often implicated in rosacea.

Research

Clinical Evidence

High confidence
Effective range 4–4%
Optimal

4%

Key findings

  1. 01 A 4% Quassia amara extract topical gel demonstrated superior efficacy and safety in treating facial Seborrheic Dermatitis compared to 2% ketoconazole and 1% ciclopiroxolamine, in a 60-patient study.
  2. 02 Topical application of 4% Quassia amara extract gel proved effective across various grades of rosacea, yielding results comparable to established treatments like metronidazole and azelaic acid over 6 weeks in a 30-patient trial.
  3. 03 Formulations containing 4% Quassia amara wood extract significantly decreased Demodex spp. populations in rosacea patients, correlating to approximately 0.03% quassin content.
  4. 04 After a 42-day course, a 4% Quassia amara extract significantly reduced P. acnes colony-forming units by 58% and Staphylococcus coagulase positive by 50.8% on the skin.

Transparency

Dusting Analysis

Not commonly dusted

No data available regarding dusting potential or specific thresholds.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for topical application in cosmetic products. However, specific data for use during pregnancy and breastfeeding is insufficient, and professional medical advice is recommended for these individuals. Patch testing is advised to rule out individual sensitivities.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Quassia amara wood is a highly valuable botanical extract, offering targeted efficacy against inflammatory skin conditions, acne-causing bacteria, and Demodex mites, while also providing broad-spectrum skin benefits.

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