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PYRIDOXINE TRIS-HEXYLDECANOATE.

Valuable CAS - / HUMECTANT

Pyridoxine Tris-Hexyldecanoate is a stable, oil-soluble vitamin B6 derivative engineered to significantly enhance skin hydration and fortify the skin barrier. It effectively modulates sebum production, provides antioxidant protection, and offers soothing benefits, making it a versatile ingredient for diverse skin concerns.

Moisturizer Humectant Sebum Regulator Antioxidant Barrier Repair Soothing Acne Improvement

Science

This oil-soluble vitamin B6 derivative operates by bolstering the skin's intrinsic moisturizing capabilities. It actively promotes the synthesis of filaggrin and loricrin, crucial amino acid precursors that contribute to the Natural Moisturizing Factor (NMF). This action strengthens the skin barrier and minimizes transepidermal water loss. Additionally, it provides sebum control through 5α-reductase inhibition, exhibits antioxidant properties, and supports skin repair and soothing processes.


Research

High confidence
Effective range N/A
Optimal

1%

Key findings

  1. 01 Clinical trials demonstrated that at a 1% concentration, it significantly improved skin hydration by boosting filaggrin synthesis, thereby increasing the skin's amino acid content.
  2. 02 Further clinical testing confirmed its effectiveness in sebum regulation, aiding in acne improvement, promoting skin repair, and delivering soothing benefits.

Transparency

Not commonly dusted

No data suggests this ingredient is commonly associated with dusting concerns.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This derivative exhibits high stability against heat and oxygen, ensuring product integrity. It demonstrates excellent transdermal absorption and oil solubility, with reduced susceptibility to color degradation. For optimal preservation, store sealed in a cool, dry place, shielded from light and heat.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not yet reviewed this ingredient for safety.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Pyridoxine Tris-Hexyldecanoate is a valuable multifunctional ingredient, clinically proven to enhance skin hydration, strengthen the barrier, regulate sebum, and provide soothing effects across all skin types.


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