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Moumoujus

PUNICA GRANATUM SEED CELL CULTURE LYSATE.

Valuable / SKIN CONDITIONING

Derived from pomegranate seeds, Punica Granatum Seed Cell Culture Lysate is a potent ingredient recognized for its extensive skin benefits. It actively targets pigmentation irregularities, enhances overall skin luminosity, and offers robust antioxidant protection against environmental stressors, particularly sun exposure.

Summary

Antioxidant Skin-Conditioning Brightening Lightening Anti-aging Tone Evening Hydrating

Science

Mechanism of Action

This ingredient functions by combating pigmentation flaws and oxidative stress, primarily due to its rich content of hydrobenzoic acids, gallotannins, and ellagitannins, which act as powerful antioxidants. Pomegranate-derived compounds also exhibit anti-comedogenic, anti-microbial, and anti-inflammatory properties, potentially by preserving or restoring crucial extracellular matrix components like collagen, elastin, and hyaluronic acid, and by modulating key signaling pathways.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A proprietary blend containing Punica Granatum Seed Cell Culture Lysate (LUMINIA GRANATUM) has demonstrated significant brightening and lightening effects, targeting pigmentation flaws, dark spots, and uneven skin tone, while also providing protection against oxidative stress and photo-induced pigmentation.
  2. 02 Related studies on topically applied pomegranate seed oil showed a notable increase in dermis thickness by 14.85%, hydration by 30.32%, and stratum corneum elasticity by 9.75% in 20 volunteers over 6 weeks.
  3. 03 Another proprietary Punica granatum extract (Grantria®) was clinically proven to reduce crow's feet wrinkles, tactile roughness, and forehead fine lines, simultaneously improving skin radiance, tone evenness, moisturization, elasticity, and firmness over 60 days, alongside a 3% reduction in tyrosinase biomarker levels.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has determined that current data is insufficient to establish the safety of Punica Granatum Seed Cell Culture Lysate for cosmetic use, requesting further information on manufacturing, composition, systemic toxicity, and dermal irritation/sensitization. However, other forms of Punica granatum, such as essential oils and natural extracts, are recognized as Generally Recognized As Safe (GRAS) by the US FDA for food consumption.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Punica Granatum Seed Cell Culture Lysate offers significant brightening, anti-aging, and antioxidant benefits across all skin types, though regulatory safety data is currently limited for the specific cell culture lysate.

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