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Moumoujus

PUNICA GRANATUM GLYCERIDES.

Valuable CAS - / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING, SURFACTANT - CLEANSING

Punica Granatum Glycerides are plant-derived esters obtained from the pomegranate fruit, Punica granatum. This versatile ingredient functions primarily as a skin conditioner, emollient, and antioxidant, harnessing the fruit's rich polyphenol content to support comprehensive skin health.

Summary

Antioxidant Skin Conditioning - Emollient Surfactant - Cleansing Surfactant - Emulsifying Anti-inflammatory Collagen Boosting Skin Brightening Hydrating Cell Regeneration

Science

Mechanism of Action

Derived from pomegranate, Punica Granatum Glycerides are believed to deliver the fruit's established benefits through multiple mechanisms. Its potent antioxidant activity stems from abundant polyphenols and anthocyanins, which combat free radicals and mitigate oxidative stress, thereby reducing visible signs of aging. The ingredient also exhibits anti-inflammatory properties, contributing to skin soothing. It is understood to encourage collagen synthesis, leading to improved skin elasticity and a reduction in fine lines and wrinkles. Pomegranate derivatives are known to enhance skin hydration and firmness, and contribute to a brighter complexion by inhibiting melanin production through compounds like ellagic acid and punicalagin. Additionally, it supports cellular repair and regeneration in the skin's upper layers and may offer astringent, anti-comedogenic, and antimicrobial effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 60-day human study observed significant decreases in melanin content when using a 4% concentration of concentrated pomegranate juice in a water/oil emulsion.
  2. 02 In vitro studies on Punica Granatum Fruit Extract demonstrated a reduction in melanin content by approximately 40% to 60% at concentrations of 50-100 µg/ml.
  3. 03 An in vitro study of skin organ culture indicated that Punica Granatum peel extract and cold-pressed seed oil (at 0.05 µL/mL and 0.5 µL/mL) promoted skin repair, inhibited matrix metalloproteinase-1 synthesis by dermal fibroblasts, and displayed antioxidant, anti-inflammatory, and anticarcinogenic activities.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Optimal pH range specifically for Punica Granatum Glycerides is not available in the provided data. Pomegranate seed oil, the base for these glycerides, can traditionally present challenges such as an unpleasant odor and a gel-like consistency if not adequately stabilized.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While Punica Granatum Glycerides itself has not been specifically evaluated by the Cosmetic Ingredient Review (CIR) Expert Panel in the provided information, related pomegranate-derived ingredients, including various extracts and seed oils, have been concluded as safe for cosmetic use. For instance, Punica Granatum Seed Extract is safe up to 0.3% and Punica Granatum Fruit Extract up to 0.1% in certain leave-on products. Pomegranate extracts are also generally recognized as safe (GRAS) by the US FDA for food use. Overall, general Punica Granatum Extract is considered safe for topical application, though a patch test is recommended for individuals with known sensitivities.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Punica Granatum Glycerides is a valuable ingredient, offering broad benefits rooted in pomegranate's antioxidant, anti-inflammatory, and skin-brightening properties, despite direct clinical data for this specific glyceride form being limited.

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