Science
Mechanism of Action
This extract operates via multiple mechanisms to enhance skin health. It is particularly noted for its ability to regulate critical skin barrier factors such as filaggrin, involucrin, and loricrin. Furthermore, it inhibits the JAK/STAT signaling pathway by suppressing JAK/STAT phosphorylation, which is typically stimulated by inflammatory interleukins (IL-4/IL-13). This action effectively reduces inflammatory responses and decreases epidermal thickness often associated with irritated skin. Beyond its anti-inflammatory effects, the extract exhibits antimicrobial activity against common skin microflora like Propionibacterium acnes and Pityrosporum ovale. It also contributes to sebum harmonization, provides a subtle moisturizing effect, and offers antioxidant protection against environmental stressors.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Studies on Pulsatilla koreana Nakai extract, a closely related species, demonstrated alleviation of atopic dermatitis-like symptoms in mice by regulating skin barrier factors and inhibiting the JAK/STAT pathway. This resulted in the suppression of inflammatory factors and a decrease in epidermal thickness.
- 02 Pulsatilla Koreana extract is known to harmonize sebum secretion, offer subtle moisturizing power, and is considered suitable for extremely sensitive or allergic skin.
Transparency
Dusting Analysis
Pulsatilla Tongkangensis Extract offers a broad spectrum of well-documented benefits including anti-inflammatory, antimicrobial, and skin-barrier support, indicating it is typically included for its active properties rather than as a minimal 'dusting' ingredient.
The Formula
Formulation
Stability
Specific stability data for Pulsatilla tongkangensis Extract is not extensively documented. However, certain components found in other Pulsatilla species, such as protoanemonin, can be unstable in aqueous extracts, particularly when exposed to high concentrations, light, and elevated temperatures. Macerates of P. alpina have been prepared at pH 7.2, suggesting this as a potential reference point for formulation pH.
Synergies
- Often used as part of natural preservative systems, such as EURO-NApre, where it is combined with Zanthoxylum Piperitum and Usnea Barbata.
Safety
Safety Profile
While the fresh Pulsatilla plant contains protoanemonin, a lactone that can act as an irritant and cause allergic dermatitis, this compound typically dimerizes to less toxic anemonin when the plant is dried and processed. In cosmetic formulations, Pulsatilla Koreana Extract, a closely related ingredient, is often listed as 'Irritant Free' by SkinSAFE and is reported to be suitable for extremely sensitive skin. No specific CIR, SCCS, or FDA safety assessments were found for Pulsatilla tongkangensis Extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pulsatilla Tongkangensis Extract is a valuable botanical ingredient, offering robust anti-inflammatory, barrier-supporting, and sebum-regulating properties, making it highly beneficial for sensitive, irritated, and acne-prone skin types.
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References
Sources