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Moumoujus

PUERARIA LOBATA ROOT EXTRACT.

Valuable CAS 223748-08-1 / HUMECTANT

Pueraria Lobata Root Extract, derived from the Kudzu plant, is a multi-functional botanical ingredient rich in isoflavones and triterpenoids. It is clinically recognized for its profound antioxidant, anti-aging, and skin-conditioning properties, contributing to enhanced skin elasticity and overall skin health.

Summary

Antioxidant Skin-Conditioning Agent Humectant Moisturizer Anti-Aging Anti-inflammatory Firming Agent Brightening Agent Sebum Regulator

Science

Mechanism of Action

This extract leverages its rich composition of isoflavones, including puerarin, daidzein, and genistein, along with triterpenoids, to exert its effects. It functions as a potent antioxidant by effectively neutralizing free radicals, thereby protecting cellular integrity and preventing the degradation of vital collagen and elastin fibers. Its anti-inflammatory capabilities reduce redness and soothe irritation through the inhibition of pro-inflammatory mediators. The phytoestrogenic compounds stimulate collagen and elastin synthesis, leading to improved skin firmness, elasticity, and a reduction in the appearance of fine lines and wrinkles. Additionally, it exhibits humectant properties, aiding in moisture retention and hyaluronic acid production, contributes to skin brightening by inhibiting tyrosinase, and may assist in regulating sebum production for balanced skin.

Research

Clinical Evidence

High confidence
Effective range 1–5%
Optimal

1-5%

Key findings

  1. 01 Demonstrated efficacy in enhancing skin elasticity, mitigating the appearance of wrinkles, and improving overall skin brightness in cosmetic formulations.
  2. 02 Significantly reduced intracellular reactive oxygen species (ROS) levels and boosted collagen synthesis in UVB-irradiated human dermal fibroblasts, indicating robust photoaging inhibition and maintenance of hyaluronic acid levels.
  3. 03 Exhibited strong antioxidant and anti-melanin synthesis activities, while also showing high cell viability (above 97%) and no toxicity in melanoma cells.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
1%
Red flag below
below 1%

Pueraria Lobata Root Extract demonstrates robust clinical efficacy within a 1-5% concentration range. Formulations containing less than 1% of this ingredient may not deliver the full spectrum of its observed benefits, suggesting potential under-dosing for marketing rather than performance.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Proper stabilization is essential to preserve the extract's efficacy over its shelf life.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as safe for topical application with no significant reported side effects. Patch testing is recommended for individuals with sensitive skin. Due to its phytoestrogen content, pregnant or breastfeeding individuals should consult a healthcare professional prior to use. A study on P. lobata stem extract indicated no adverse skin responses in human safety tests.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Pueraria Lobata Root Extract is a valuable, multi-beneficial ingredient, offering significant antioxidant, anti-aging, and skin-conditioning effects, suitable for a broad range of skin types and concerns at concentrations between 1-5%.

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