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Moumoujus

PTEROCARPUS MARSUPIUM BARK EXTRACT.

Insufficient Data CAS 84604-08-0 / HAIR CONDITIONING

Pterocarpus Marsupium Bark Extract is a multi-functional botanical ingredient recognized for its potent antioxidant, anti-inflammatory, and anti-glycation properties. It actively protects skin from oxidative damage and addresses various signs of aging, while also contributing to skin brightening. Its comprehensive action supports overall skin health and resilience.

Summary

Antioxidant Anti-inflammatory Skin brightening Anti-aging Anti-glycation Wound healing Astringent Hair conditioning

Science

Mechanism of Action

This extract acts as a powerful antioxidant by effectively inhibiting free radicals and significantly reducing reactive oxygen species (ROS), thereby protecting cells from oxidative damage. It possesses anti-inflammatory capabilities, evidenced by decreased PGE2 production which indicates COX-2 specific inhibition, helping to soothe skin inflammation and delay aging processes. The ingredient also exhibits anti-glycation effects to further combat skin aging. For skin brightening, it suppresses melanin and tyrosinase activity and inhibits melanogenesis by activating nicotinamide nucleotide transhydrogenase (NNT), which lowers ROS levels. Furthermore, it enhances glutathione (GSH) levels, shifting melanin synthesis towards lighter pheomelanin. Some constituents may promote skin repair and regeneration, aiding in wound healing, and it functions as a natural astringent to tone skin and reduce the appearance of enlarged pores.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data suggests this ingredient is commonly 'dusted' or used at concentrations below its effective threshold.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Specific optimal pH range and detailed stability information are not provided in the available research data.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

As of September 2010, the Cosmetic Ingredient Review (CIR) reported insufficient data to support the safety of Pterocarpus Marsupium Bark Extract. However, human data indicates a lack of irritation, suggesting potential suitability for sensitive skin. The EWG Skin Deep database rates its concerns for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity as 'Low', but notes that EWG VERIFIED products require adequate substantiation for its inclusion.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Pterocarpus Marsupium Bark Extract presents a promising multi-functional profile based on its mechanistic actions and studies on related compounds, its overall safety remains incompletely assessed by the CIR, necessitating further rigorous substantiation for precise formulation and confident use.

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