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PSOPHOCARPUS TETRAGONOLOBUS ROOT EXTRACT.

Valuable / SKIN PROTECTING

Psophocarpus Tetragonolobus Root Extract, derived from the winged bean, is a multi-functional botanical extract rich in potent antioxidants and anti-inflammatory compounds. It actively safeguards skin from free radical damage, calms inflammatory responses, and supports collagen synthesis to enhance elasticity and reduce visible signs of aging.

Antioxidant Anti-inflammatory Anti-aging Skin elasticity booster Collagen production booster Wrinkle reduction Hyperpigmentation reduction Epidermal differentiation support

Science

This extract functions through several key pathways: potent antioxidant activity from its richness in bioactive molecules such as polyphenols, flavonoids, and vitamins A/C, which neutralize free radicals and oxidative stress. Its anti-inflammatory action suppresses pro-inflammatory mediators including IL-1β, IL-6, TNF-α, COX-2, and iNOS, often by inhibiting NF-κB and STAT3 signaling pathways. Furthermore, its vitamin C content promotes collagen production for improved elasticity, while vitamin A aids in diminishing the appearance of sagging, wrinkles, and hyperpigmentation, collectively enhancing epidermal differentiation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro analysis showed efficient suppression of IL-1β, TNF-α, and IL-6 mRNA expression, and inhibition of COX-2 and iNOS protein expression at 300 µg/mL (0.03%), indicating strong anti-inflammatory potential.
  2. 02 Another in vitro study demonstrated significant antioxidant activity (7.27% using the FTC method) with an ethyl acetate extract at 0.05%.
  3. 03 A 5-week oral administration study of a winged bean seed extract in a human skin lichenification model inhibited wrinkle formation and modulated genes linked to epidermal differentiation and inflammation, suggesting systemic benefits relevant to skin health.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Optimal pH range for cosmetic stability is not documented in available literature. Information on pH largely pertains to protein extraction from seeds (optimal around pH 12, minimum extractability at pH 4) or soil conditions for plant growth (cannot withstand pH < 5.5), which are not directly applicable to the root extract's stability in a skincare formulation.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While winged bean (Psophocarpus tetragonolobus) and its various parts are generally considered safe for human consumption and have a history of use in traditional medicine and cuisine, its safety specifically for topical cosmetic applications has not been formally assessed by regulatory bodies like CIR or SCCS.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Psophocarpus Tetragonolobus Root Extract is a valuable botanical ingredient offering significant antioxidant and anti-inflammatory benefits, with potential to improve skin elasticity and reduce signs of aging based on in vitro and oral studies.


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