Science
Mechanism of Action
This unique Antarctic marine glycoprotein enhances skin's intrinsic ability to retain moisture by binding water molecules and actively preventing transepidermal water loss. PFE precisely targets dermal protein synthesis, significantly boosting both Collagen I (by 128%) and Collagen IV (by 81%) production, alongside an increase in Elastin levels (by 31%), thereby fortifying skin structure and elasticity. It further promotes tissue regeneration by stimulating fibroblast adhesion and keratinocyte growth, offers antioxidant defense against environmental aggressors, and strengthens the skin's natural protective barrier. Additionally, PFE can regulate excess sebum production by modulating the Melanocortin 5 receptor and provides cryoprotective effects, shielding skin from temperature extremes.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Increased skin hydration by 14.8% in cold weather when formulated as a cream.
- 02 Decreased the depth of wrinkles around the eyes by up to 50% in some cases when applied in an oil-in-water emulsion.
- 03 Increased Collagen I production by 128%, Collagen IV production by 81%, and Elastin levels by 31% after 15 days in in vitro tests.
- 04 Showed significant reductions in the depth of upper lip wrinkles after 1-4 weeks.
- 05 Reduced skin gloss and significantly decreased the number of active follicles (by 9.5%) and their total surface (by 27.2%) after 28 days for oily skin control.
Transparency
Dusting Analysis
Pseudoalteromonas Ferment Extract's robust clinical data, demonstrating measurable efficacy at specific concentrations for multiple skin benefits, indicates it is a genuine active ingredient rather than a 'dusting' component.
The Formula
Formulation
Stability
Optimal stability is observed within a pH range of 5.5 to 6.5. To preserve its bioactivity, it is recommended to incorporate this ingredient into formulations during the final phase of manufacturing. Store in a cool, dark, and dry environment.
Conflicts
- Highly concentrated acids
Safety
Safety Profile
General safety assessments suggest its byproducts are nontoxic and nonirritating. EWG Skin Deep rates it with 'LOW' concerns for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity. While generally considered safe for all skin types, individuals susceptible to Malassezia folliculitis (fungal acne) may react to ferments, though individual responses vary.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pseudoalteromonas Ferment Extract is a scientifically validated, multi-benefit ingredient offering significant hydration, potent anti-aging effects through collagen and elastin stimulation, and effective oil regulation for a visibly healthier and more resilient complexion.
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