Science
Mechanism of Action
PRUNUS SPINOSA FRUIT JUICE acts primarily as a potent antioxidant by actively scavenging free radicals and reducing oxidative stress, attributed to its high content of polyphenols, anthocyanins, phenolic acids, flavonoids, and Vitamin C. Its anti-inflammatory effects stem from modulating immune cell functions, decreasing the release of reactive oxygen species (ROS), TNF-α, and elastase (ELA-2), while simultaneously promoting IL-10 secretion. The juice also exhibits antimicrobial activity, particularly against Gram-positive bacteria, and offers skin conditioning benefits, including moisturizing and astringent qualities from its tannin content. Additionally, its phenolic compounds provide photoprotective effects by absorbing UV radiation.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 In an oil-in-water formulation, this concentration demonstrated significant moisturizing potential, with polymer entrapment not impeding its efficacy.
- 02 Ex vivo studies on human neutrophils and monocytes revealed a dose-dependent modulation of pro-oxidant and pro-inflammatory functions, with effects observed from 5 µg/mL. Cellular safety was consistently confirmed across a broad concentration spectrum.
- 03 In vitro testing showed this concentration effectively inhibited over 50% of the growth of Gram-positive bacteria, specifically Enterococcus faecalis and Staphylococcus aureus.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The key active compounds, anthocyanins, are susceptible to oxidation and degradation by various environmental factors including alkaline pH, elevated temperature, light exposure, and oxygen, which can induce a color shift from red-violet to red-brown. Processing methods involving aeration, such as air-drying, can also lead to the oxidation of flavonoids and Vitamin C. Optimal stability is observed within its natural acidic pH range of 4.28 to 4.34.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Prunus Spinosa Fruit Juice. However, a related ingredient, Prunus Spinosa Fruit Extract, is listed by the FDA as Generally Recognized As Safe (GRAS) for food use. EWG Skin Deep assesses Prunus Spinosa Fruit Juice with low concerns across categories including cancer, allergies & immunotoxicity, developmental and reproductive toxicity, and use restrictions. Cellular safety has been confirmed in a wide range of concentrations in various studies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Prunus Spinosa Fruit Juice is a valuable multi-functional ingredient, offering robust antioxidant, anti-inflammatory, and moisturizing benefits supported by scientific evidence and a favorable safety profile.
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References
Sources