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Moumoujus

PRUNUS MUME BRANCH EXTRACT.

Valuable / SKIN CONDITIONING

Prunus Mume Branch Extract is a multifaceted botanical ingredient rich in antioxidants, offering comprehensive protection against environmental stressors and supporting skin vitality. It is recognized for its ability to combat glycation, inhibit melanin production, and promote skin rejuvenation.

Summary

Antioxidant Anti-aging Skin Brightening Anti-inflammatory Moisturizing Oil Balancing Firming UV Protection Support

Science

Mechanism of Action

PRUNUS MUME BRANCH EXTRACT, along with other Prunus mume extracts, exerts its effects through a range of bioactive compounds, including flavonoids and phenolic acids, which deliver potent antioxidant benefits by neutralizing free radicals. The extract helps protect skin structural proteins from glycation and aids in the decomposition of Advanced Glycation End products (AGEs), contributing to improved skin tone and firmness. It also exhibits anti-inflammatory properties, helps regulate oil production, strengthens the skin's protective barrier, and supports skin regeneration. Furthermore, it inhibits melanin production, contributing to a brightening effect, and has been shown to increase collagen levels while downregulating matrix metalloproteinases (MMP-1 and MMP-13), which are key factors in UV-induced skin aging.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Prunus Mume fruit extract inhibits melanin production, contributing to skin brightening.
  2. 02 Prunus Mume fruit extract protects skin structural proteins against glycation, reduces AGEs (improving yellowish pigmentation, especially during menopause), and enhances skin tone and firmness. It is effective across various stages of glycation.
  3. 03 Prunus Mume ripened seed extract (PmRS) demonstrated protective effects against UV-induced skin aging in mice, including increased collagen levels and reduced skin thickness. In vitro, it prevented UVB-induced reactive oxygen species generation in HaCaT cells and downregulated MMP-1 and MMP-13 expression.
  4. 04 General Prunus Mume extract (PME) did not exhibit cytotoxic effects on murine B16 melanoma cells at concentrations below 1500 μg/mL.
  5. 05 General Prunus Mume extract (PME) at a concentration of 1000 μg/mL neutralized over 45% of free radical activity.
  6. 06 General Prunus Mume extract inhibited melanin production through the regulation of melanogenesis-associated protein expression in melanocytes.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Prunus Mume fructus extract has demonstrated stability under tested conditions in pharmacokinetic studies, with a relative standard deviation lower than 13.7%.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

No specific CIR, SCCS, or FDA regulatory status is available for PRUNUS MUME BRANCH EXTRACT. General Prunus mume extracts have shown no significant cytotoxicity in vitro at concentrations up to 200 µg/mL or <1500 μg/mL, and Prunus mume ripened seed extract was non-toxic in alternative animal tests. However, individuals with allergies to plants in the Rosaceae family may experience sensitivity or allergic reactions, such as skin irritation or itching, particularly with flower extracts.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PRUNUS MUME BRANCH EXTRACT is a valuable ingredient, offering broad benefits from antioxidant and anti-glycation properties to melanin inhibition and anti-aging effects, suitable for a wide range of skin types.

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