Science
Mechanism of Action
This extract operates through multiple pathways to optimize skin health. Its high concentration of flavonoids, polyphenols, and tannins acts synergistically to neutralize free radicals, thereby effectively reducing oxidative stress and the visible signs of premature aging. Anti-aging efficacy is further evidenced by its in vitro capacity to boost sirtuin SIRT1 protein expression. Additionally, the extract demonstrates anti-tyrosinase activity, which directly supports the reduction of melanin biosynthesis for a brightening effect. It also exerts anti-inflammatory properties to soothe irritation and redness, alongside functioning as a skin conditioning agent to fortify the skin's barrier against external aggressors and dehydration. Antimicrobial activities have also been observed.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In an in vitro assay, cherry tree branch extract demonstrated significant antioxidant activity, registering an IC50 of 15.39 ± 0.19 µg/mL, indicating superior potency compared to trolox.
- 02 An in vitro study revealed that cherry tree branch extract exhibited robust anti-tyrosinase activity, with an IC50 of 0.025 ± 0.003 mg/mL, proving more active than kojic acid in reducing melanin production.
- 03 In vitro testing of Actipone® Sweet Cherry Tree Wood (a Prunus avium L. wood extract) confirmed its anti-oxidant, anti-irritant, and anti-aging properties, specifically through an observed increase in sirtuin SIRT1 protein expression.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The inherent antioxidant capacity of Prunus Avium Wood Extract can aid in stabilizing cosmetic formulations and preserving the integrity of other active ingredients. Optimal extraction conditions for maximizing its antioxidant properties were identified as 70% aqueous ethanol at 70 °C.
Safety
Safety Profile
Generally regarded as safe for use in cosmetic and personal care products. GHS classification according to OSHA HCS found no specific hazards. While oral, dermal, and inhalation toxicity data are not determined, individuals with known allergies to cherry wood or extremely sensitive skin should exercise caution.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Prunus Avium Wood Extract is a valuable, multi-functional ingredient with scientifically supported in vitro efficacy across antioxidant, anti-aging, brightening, and conditioning benefits, making it suitable for a broad spectrum of skin types.
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References
Sources