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PROPOLIS EXTRACT.

Valuable CAS 85665-41-4 / SKIN CONDITIONING

Propolis Extract is a natural resinous compound, recognized for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It actively supports skin healing and regeneration while enhancing elasticity and hydration, making it a multifaceted ingredient for various skin concerns.

Antioxidant Anti-inflammatory Antimicrobial Skin-Conditioning Humectant Wound healing Soothing Protective

Science

Propolis Extract acts through several key mechanisms: its rich phenolic compounds, including caffeic acid, effectively reduce inflammation and calm redness by inhibiting inflammatory pathways. As a robust antioxidant, it defends skin cells from environmental damage and oxidative stress, thereby mitigating premature aging. Its broad-spectrum antimicrobial action against bacteria, fungi, and viruses makes it beneficial for managing blemishes and soothing irritated skin. Furthermore, Propolis promotes collagen production, which enhances skin elasticity and firmness, and functions as a humectant to attract and retain moisture, strengthening the skin's natural barrier. It also stimulates new cell regeneration and accelerates the healing process.


Research

High confidence
Effective range 1.5–5%
Optimal

N/A

Key findings

  1. 01 A 1.5% concentration demonstrated a 25% reduction in wrinkle depth after 28 days of use, which increased to a 34% reduction with a 3% concentration.
  2. 02 At 2%, Propolis Extract significantly reduced the total plate count of microorganisms in hand cream formulations, showcasing its biopreservative capabilities.
  3. 03 A 5% concentration exhibited bactericidal activity against Staphylococcus aureus in a cream formulation and promoted the closure of diabetic foot wounds.
  4. 04 Phenolic compounds from a 3% soft extract were observed to penetrate the epidermis and dermis, achieving approximately 1.5% penetration in cream formulations and 2% in ointments.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 3.5 – 5.5
0 7 14

Stability

Propolis Extract is scarcely soluble in water, but highly soluble in ethanol, with 70-75% ethanol being an effective solvent for extracting active flavonoids. While natural beeswax components are oil-soluble, specialized extraction methods employing glycerol, plant oils, or PEG-based solvents can yield water-soluble or oil-soluble extracts, making it adaptable for diverse cosmetic formulations.

Conflicts

  • Fragrances (potential irritation)
  • Essential oils (potential drying/irritation)

Safety

CIR Status
Currently being reviewed
Sensitization risk High

Propolis Extract is generally considered safe for cosmetic use, presenting as light on the skin and non-comedogenic. However, it is a known contact allergen and can induce allergic reactions, particularly in individuals with documented allergies to bee products. Patch testing is strongly recommended prior to widespread application. Due to rising allergy concerns, the CIR Expert Panel added Propolis Extract to its 2023 priorities list for an accelerated review.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Propolis Extract is a highly valuable, multifunctional ingredient for targeted skincare, offering significant benefits across various skin concerns, though caution is advised due to its known allergenic potential.


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