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Moumoujus

PRISTANE.

Avoid CAS 1921-70-6 / SKIN CONDITIONING

Pristane is a branched-chain hydrocarbon, classified as an alkane oil. While it has been theoretically noted for emollient properties, its primary and well-documented use in scientific research is as a potent inflammation-inducing agent. Due to significant safety concerns, its inclusion in cosmetic formulations for direct skin application is highly problematic.

Summary

Emollient

Science

Mechanism of Action

As a hydrocarbon, Pristane could form an occlusive layer on the skin, potentially aiding moisture retention and improving skin texture. However, its prominent biological mechanism involves acting as an immunologic adjuvant, eliciting severe inflammatory responses and inducing autoimmune conditions in research models.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Pristane is considered stable, maintaining its integrity for at least 2 years when stored at +4°C and protected from light and moisture. The pH value is not applicable for this ingredient.

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not published a dedicated safety assessment for Pristane. While historical mentions exist within reviews of related hydrocarbons, this does not constitute a safety clearance for Pristane itself. Safety data sheets indicate a high potential for skin irritation, leading to severe reactions such as redness, swelling, vesicles, scaling, thickening, and potential ulceration upon prolonged or repeated exposure. The FDA does not mandate pre-market approval for cosmetic ingredients, placing the responsibility for product safety on manufacturers.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Pristane is a highly irritating substance primarily used in research to induce severe inflammation and autoimmune conditions, rendering it entirely unsuitable for safe cosmetic application.

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