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PRINSEPIA UTILIS SEED EXTRACT.

Valuable CAS - / ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING

Prinsepia Utilis Seed Extract is a botanical ingredient derived from the seeds of the Prinsepia Utilis plant, offering a multi-faceted approach to skin health. It is scientifically shown to enhance the skin's natural moisturizing factors, fortify the barrier, and provide significant soothing and antioxidant protection, making it ideal for comprehensive skin resilience.

Summary

Skin Conditioning Moisturizing Skin Barrier Support Anti-inflammatory Antioxidant Astringent

Science

Mechanism of Action

This extract actively improves skin hydration by stimulating the synthesis of crucial epidermal ceramides and hyaluronic acid. It strengthens the skin's inherent protective capabilities by enhancing the expression of tight junction proteins, specifically Claudin-3, -4, and -5, thereby reducing trans-epidermal water loss. Beyond barrier support, it promotes cell migration for skin repair, increases skin thickness, and exhibits anti-inflammatory effects through the inhibition of IL-6 and TNF-α. Furthermore, it delivers antioxidant protection, with its unsaturated fatty acids also contributing to regulated skin permeability.

Research

Clinical Evidence

High confidence
Effective range 0.01–3%
Optimal

1%

Key findings

  1. 01 Prinsepia Utilis oil (1-2%) significantly increased epidermal ceramide and hyaluronic acid synthesis, demonstrating robust moisturizing efficacy.
  2. 02 A polysaccharide extract promoted cell migration and increased skin thickness in reconstructed human epidermis models, while decreasing trans-epidermal water loss (TEWL) and boosting hyaluronic acid content. It also enhanced tight junction protein expression (Claudin-3, -4, -5), indicating strong barrier repair capabilities.
  3. 03 WActive® Prinsepia Oil (0.01-2%) demonstrated anti-inflammatory effects in vitro, inhibiting IL-6 synthesis by 22.8% and TNF-α by 49.2%.
  4. 04 Micronized Prinsepia Utilis Royle seed powder (0-3.0 wt%) exhibited dose-dependent antioxidant activity in emulsions, with DPPH radical scavenging rates increasing from 9.99% to 91.71%.

Transparency

Dusting Analysis

Not commonly dusted

There is no specific data suggesting that Prinsepia Utilis Seed Extract is commonly 'dusted' or used in sub-efficacious concentrations merely for label appeal. Clinical studies report efficacious percentages for its various benefits.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Formulations containing higher concentrations of Prinsepia Utilis oil, which contains fatty acids, may present preservation challenges. A concentration of 1% is suggested for optimal stability in skincare applications while maintaining efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not formally reviewed Prinsepia Utilis Seed Extract or Oil. Acute toxicity studies (OECD guidelines 423) found Prinsepia Utilis Seed Oil to be non-toxic, and it is rated as 'Irritant Free' by SkinSAFE. Dermal toxicity for the extract specifically is not determined, but overall data suggests low risk.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Prinsepia Utilis Seed Extract is a valuable ingredient, demonstrated to significantly improve skin hydration and barrier function, alongside offering notable anti-inflammatory and antioxidant benefits.

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