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PPG-24-GLYCERETH-24.

Valuable CAS 51258-15-2 / SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PPG-24-GLYCERETH-24 is a synthetic, glycerin-based compound primarily utilized as an emulsifier and surfactant in skincare formulations. It enables the stable blending of oil and water, enhancing product consistency and efficacy. Additionally, it functions as a solubilizer and solvent, optimizing ingredient dispersal and formulation texture.

emulsifying solvent surfactant cleansing solubilizer

Science

This ingredient reduces the surface tension of liquids, a key function of its surfactant properties, by bridging immiscible components like oils and water. Its molecular structure, a polyoxypropylene and polyoxyethylene ether of glycerin, features both lipophilic (oil-attracting) and hydrophilic (water-attracting) regions, which are crucial for forming stable emulsions. As a liquid polypropylene glycol derivative, it also acts as a solvent and solubilizer, facilitating the dissolution and uniform distribution of other ingredients. Notably, it exhibits a beneficial affinity for the skin, and when paired with glycerin, it has been observed to enhance moisturizing effects.


Research

Low confidence
Effective range 1–10%
Optimal

2%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Synergies

  • glycerin (to boost moisturizing effects)

Conflicts

  • other problematic ingredients (may increase irritation likelihood)

Safety

CIR Status
Safe as used
Max tested
10%
Sensitization risk Low

The CIR Expert Panel has concluded that polypropylene glycols (PPGs) with a value of ≥3, including PPG-24-GLYCERETH-24, are safe for cosmetic use when properly formulated to be non-irritating. However, independent research specifically on this ingredient is limited, with most information provided by suppliers. The EWG notes a low to moderate concern for non-reproductive organ system toxicity. SkinSAFE identifies it as free of common irritants, and it is generally considered non-irritating, although potential for irritation may increase when combined with other problematic ingredients. No specific SCCS opinion or FDA status for this particular ingredient was found.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

PPG-24-GLYCERETH-24 is a valuable formulation aid, providing essential emulsifying, solubilizing, and solvent properties while generally demonstrating good skin compatibility and a low irritation risk at standard usage levels.


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