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PPG-2-CETETH-12.

Valuable CAS 37311-01-6 (generic), 9087-53-0 (generic) / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PPG-2-CETETH-12 is a multifunctional polyether compound utilized in precision skincare formulations for its powerful surfactant and emulsifying capabilities. It ensures the stability and homogeneity of emulsions, preventing phase separation, and aids in the uniform dispersion of ingredients.

Summary

Emulsifying Surfactant

Science

Mechanism of Action

This ingredient functions by significantly lowering the interfacial tension between immiscible liquids, such as oil and water, owing to its amphiphilic molecular structure containing both hydrophilic and hydrophobic segments. This action is crucial for forming and stabilizing emulsions, which are fundamental to the texture and integrity of many cosmetic products. Additionally, it acts as a solubilizer, assisting in the uniform distribution of water-insoluble components, and a wetting agent, enhancing the spreadability of products on the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

As an effective emulsifier, PPG-2-CETETH-12 is highly instrumental in creating and maintaining stable oil-in-water (O/W) emulsions. It exhibits broad compatibility with diverse oils and active ingredients and can be synergistically combined with other emulsifiers. For enhanced emulsion stability, its integration with gel-forming thickeners is often recommended.

Synergies

  • Gel-forming thickeners

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that PPG-2-CETETH-12, as part of the broader group of alkyl PEG/PPG ethers, is safe in current cosmetic uses and concentrations when formulated to be non-irritating. While a specific maximum use concentration for PPG-2-CETETH-12 is not specified in the reviewed data, related alkyl PEG/PPG ethers have reported maximum concentrations up to 10% in rinse-off products and 5% in leave-on products. It is important to note that this ingredient, like other PEG derivatives, should not be applied to broken or damaged skin due to historical reports of kidney damage associated with polyethylene glycol ingredients in burn patients. Concerns regarding potential contamination with impurities such as ethylene oxide and 1,4-dioxane exist for ethoxylated ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PPG-2-CETETH-12 is a valuable formulation ingredient, critical for emulsion stability and texture, with a generally low irritancy profile when incorporated into non-irritating product concentrations.

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