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PPG-12 DIMETHICONE.

Valuable CAS 68440-66-4 / 68554-64-3 / HAIR CONDITIONING, SKIN CONDITIONING

PPG-12 Dimethicone is a versatile silicone-polyether copolymer, recognized for its amphiphilic nature and ability to condition both skin and hair. It effectively forms a breathable, protective film on the skin, contributing to improved texture and moisture retention while also functioning as a solubilizer and solvent in cosmetic formulations.

Summary

Skin conditioning Hair conditioning Solubilizer Solvent Film former

Science

Mechanism of Action

This ingredient operates as a poly(propylene glycol) derivative of dimethicone, classified as a silicone-polyether copolymer. Its amphiphilic structure, comprising both water-attracting (hydrophilic) and water-repelling (hydrophobic) properties, allows for broad compatibility within formulations. On the skin, PPG-12 Dimethicone creates a protective, vapor-permeable film that boasts excellent spreading quality, thereby conditioning the skin and helping to maintain its healthy state. As a polyether component, it further acts as a solubilizer and solvent, aiding in the dispersion and integration of other ingredients.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

As an amphiphilic silicone-polyether copolymer, PPG-12 Dimethicone exhibits solubility in both aqueous and oil phases, facilitating its integration into diverse formulations. Its stability may be compromised by exposure to strong acid or alkali environments, a characteristic observed in similar silicone-polyether derivatives like PEG-12 Dimethicone.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has assessed PPG-12 Dimethicone within a broader group of Alkoxy Polysiloxanes, concluding its safety for use in cosmetic products, including leave-on applications. While a specific maximum use concentration for PPG-12 Dimethicone is not explicitly defined in the available data, related dimethicone crosspolymer ingredients have been deemed safe at typical concentrations. SkinSAFE rates PPG-12 Dimethicone as 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', 'Eyelid SAFE', and 'Irritant Free', indicating a very low potential for irritation or sensitization. There is no direct SCCS opinion or FDA status specifically for PPG-12 Dimethicone; however, the chemically similar PEG-12 Dimethicone has been evaluated by both the FDA and the European Commission (SCCS) and deemed safe within recommended concentrations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PPG-12 Dimethicone is a valuable, low-risk ingredient for skincare and haircare, offering effective conditioning, film-forming, and solubilizing properties suitable for all skin types.

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