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PPG-10 METHYL GLUCOSE ETHER.

Valuable CAS 61849-72-7 / HAIR CONDITIONING, SKIN CONDITIONING

PPG-10 Methyl Glucose Ether is a highly versatile polyether compound that functions as an effective emollient and humectant. It significantly boosts skin hydration by attracting and retaining moisture, concurrently improving the feel and texture of cosmetic formulations.

Summary

Hair conditioning Skin conditioning Emollient Humectant Fragrance fixative

Science

Mechanism of Action

This ingredient primarily enhances skin hydration through its water-binding properties, which helps maintain the skin's optimal condition. Beyond its direct moisturizing action, it imparts emollient benefits to aqueous systems, stabilizes fragrances, and improves the sensory experience of products. It is known to mitigate the stinging sensation in hydroalcoholic solutions and exhibits de-tackifying and solubilizing characteristics.

Research

Clinical Evidence

High confidence
Effective range 0.1–5%
Optimal

5%

Key findings

  1. 01 Recommended use levels for its humectant and emollient effects range from 0.1% to 5.0%, depending on the specific application needs.
  2. 02 A human repeated insult patch test (HRIPT) evaluated its safety profile in a face cream at a concentration of 0.8%, demonstrating good tolerance.
  3. 03 When tested undiluted at 100% concentration in human skin irritation and sensitization studies, it was classified as a mild, transient irritant.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

PPG-10 Methyl Glucose Ether can be effectively formulated with other humectants like glycerin, often resulting in synergistic performance. It enhances the sensory properties of formulations, reduces the stinging potential of hydroalcoholic products, and provides de-tackifying and solubilizing benefits. Furthermore, it has been observed to increase foam wetness and, by analogy with related compounds, may improve formulation stability.

Synergies

  • Glycerin

Safety

Safety Profile

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that PPG-10 Methyl Glucose Ether, along with other methyl glucose polyethers and esters, is safe for use in cosmetic applications at current concentrations and practices. While typical recommended concentrations are up to 5.0%, studies involving the undiluted ingredient at 100% identified it as a mild, transient irritant. The ingredient is listed in the FDA UNII database, and no specific SCCS assessment was found.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PPG-10 Methyl Glucose Ether is a valuable and well-tolerated ingredient that offers significant hydration and emollience, while also enhancing the sensory and stability profiles across a diverse range of cosmetic formulations.

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