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PPG-10-BUTETH-9.

Valuable CAS 9038-95-3 / 9065-63-8 / HAIR CONDITIONING, SKIN CONDITIONING

PPG-10-BUTETH-9 is a versatile synthetic derivative of polypropylene glycol, serving primarily as a skin conditioning agent, emollient, and solvent. It is engineered to enhance the skin's texture and appearance, specifically by reducing flaking and restoring a sense of suppleness to dry or compromised skin. This ingredient is well-regarded for its good skin tolerance and broad applicability.

Summary

Emollient Solvent Skin-Conditioning Agent

Science

Mechanism of Action

This ingredient functions by maintaining the skin in good condition through its properties as a skin conditioning agent. As a synthetic polypropylene glycol (PPG) derivative and part of the PPG Butyl Ether family, it utilizes its wide range of viscosity and solubility. In formulations, it acts as a solubilizer and solvent. On a dermatological level, it contributes to improved skin appearance by actively reducing flaking and enhancing the skin's suppleness.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Several safety assessments on related PPG Butyl Ethers highlight a low potential for irritation or sensitization. For instance, a Repeat Insult Patch Test (RIPT) with 109 subjects showed no skin irritation or sensitization from 0.75% PPG-12-Buteth-16 under semi-occlusive conditions. Similarly, aftershave products containing 2.5% PPG-26-Buteth-26 were confirmed as non-irritants or sensitizers in two 21-day home use tests involving a total of 106 subjects. Broader clinical evaluations involving 200 subjects for PPG BE800 and 112 subjects for PPG-40 Butyl Ether also concluded non-irritating and non-sensitizing properties for these family members.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

PPG-10-BUTETH-9 exhibits good water solubility, estimated at 1188 mg/L at 25°C. Polypropylene glycols and their derivatives are recognized for their excellent skin tolerance and diverse viscosity and solubility characteristics, making them flexible for various cosmetic applications. While heat tolerant, temperatures exceeding 80°C should be avoided, as observed with the related ingredient PPG-9.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
as used in current cosmetic practices%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel rigorously assessed PPG Butyl Ether ingredients, including PPG-10-BUTETH-9, and concluded their safety for cosmetic use when formulated appropriately to prevent irritation. Despite some animal data suggesting potential irritation, clinical testing has consistently shown no significant skin irritation with properly formulated products. This ingredient group is compliant with the general provisions of the European Union's Cosmetics Regulation. While no specific direct FDA cosmetic approval was found, its generic CAS number 9038-95-3 is referenced in several FDA CFR codes pertaining to indirect food additives.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PPG-10-BUTETH-9 is a valuable, low-risk ingredient adept at enhancing skin condition, providing emolliency and solvent properties, and is suitable for all skin types, with robust safety support from the CIR Expert Panel for its ingredient family.

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