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Moumoujus

PPG-1-CETETH-5.

Valuable CAS 9087-53-0 / 37311-01-6 / SKIN CONDITIONING, SURFACTANT - CLEANSING

PPG-1-CETETH-5, with research primarily focusing on PPG-5-CETETH-20, is a precision cosmetic ingredient functioning as a synthetic non-ionic surfactant, emulsifier, and emollient. It enhances product stability and spreadability while providing moisturizing benefits and a smooth skin feel.

Summary

emulsifying surfactant emollient wetting agent solubilizer humectant plasticizer dispersing agent skin permeation enhancer

Science

Mechanism of Action

This ingredient functions by reducing surface tension as a non-ionic surfactant, allowing for the stable blending of immiscible oil and water phases within formulations. As an emulsifier, it stabilizes these mixtures, improving product texture and consistency. On the skin, it forms a protective, silky film that minimizes transepidermal water loss (TEWL), thereby enhancing moisture retention and imparting a soft, smooth sensation. It also acts as a solubilizer for various ingredients, a humectant to attract moisture, a plasticizer, a wetting agent, and can disperse powders and pigments, additionally mitigating the harshness of anionic surfactants.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Microemulsions formulated with PPG-5-CETETH-20 at low surfactant concentrations, maintaining a pH between 5.0 and 5.2, were shown to act as effective skin permeation enhancers. These microemulsions significantly increased the partition and diffusion coefficients of nifedipine in the skin, suggesting potential for enhanced active ingredient delivery.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient is water-soluble and also dissolves effectively in aqueous alcoholic systems. Its molecular structure, a mixed ether of ethylene and propylene oxides, contributes to its enhanced functional properties and mildness, benefiting from the fluidity provided by propylene oxide and the water solubility from ethylene oxide. It demonstrates good compatibility with other surfactants.

Synergies

  • Compatible with other surfactants to enhance overall product stability and spreadability.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
20%
Sensitization risk Low

It is important to note that all comprehensive safety and efficacy data for 'PPG-1-CETETH-5' found during research pertain to 'PPG-5-CETETH-20', and this profile is based on that related ingredient. The Cosmetic Ingredient Review (CIR) Expert Panel concluded that PPG-5-CETETH-20 is safe for use in cosmetic applications when formulated to be non-irritating. Typical usage concentrations in cosmetic formulas range from 0.05% to 10%, with a maximum safe concentration up to 20%. A critical consideration is the potential for contamination by ethylene oxide and 1,4-dioxane, both recognized carcinogens; rigorous filtration procedures are imperative to eliminate these risks.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PPG-1-CETETH-5, drawing its profile from data on the closely related PPG-5-CETETH-20, is a highly valuable, multifunctional ingredient that optimizes formulation stability and spreadability, while delivering emollient benefits and potentially enhancing active delivery for all skin types.

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