Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

POTERIUM OFFICINALE LEAF EXTRACT.

Valuable CAS 84787-71-3 / ASTRINGENT, TONIC

Poterium Officinale Leaf Extract, also known as Sanguisorba officinalis, is a botanical powerhouse revered for its multifaceted benefits in skincare. It delivers potent antioxidant protection, calms inflammatory responses, and exhibits effective antimicrobial action, contributing to a healthier, more balanced skin environment. This extract is especially suitable for addressing concerns related to oiliness, sensitivity, and maintaining overall skin wellness.

Summary

antimicrobial tonic antioxidant astringent skin conditioning anti-inflammatory

Science

Mechanism of Action

Poterium Officinale Leaf Extract exerts its effects through several key pathways. It actively suppresses pro-inflammatory chemokine production in human keratinocytes and inhibits NF-κB/p65 translocation, thereby mediating anti-inflammatory responses. Its high antioxidant capacity effectively neutralizes free radicals, safeguarding cellular integrity. Furthermore, it demonstrates direct antibacterial and antimicrobial activity against various strains, while also acting as an astringent and tonic to refine pore appearance and promote a sense of skin well-being. Preliminary data suggests anti-wrinkle benefits potentially mediated via p38 MAPK signaling, building upon its traditional use for wound healing.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated high antioxidant activity using the ABTS•+ method.
  2. 02 Exhibited significant antibacterial activity against various bacterial strains in vitro.
  3. 03 Suppressed the production of pro-inflammatory chemokines in human keratinocytes.
  4. 04 Active constituents of Sanguisorba officinalis (from root) were shown to possess anti-wrinkle properties without exhibiting cytotoxicity.
  5. 05 Inhibited LDHA activity in vitro.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Formal safety reviews by CIR or SCCS for Poterium officinale leaf extract or Sanguisorba officinalis leaf extract are not available. However, botanical extracts are generally regulated under cosmetic guidelines. Studies evaluating Sanguisorba officinalis extract orally in mice at concentrations up to 50 mg/kg did not indicate renal or hepatic toxicity. A lack of cytotoxicity observed in anti-wrinkle studies suggests a potentially low irritancy profile for topical application.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Poterium Officinale Leaf Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-inflammatory, and antimicrobial benefits for a wide range of skin types, particularly oily and sensitive.

Related

Similar Ingredients

Finding similar ingredients…

References

Sources