POTENTILLA CHINENSIS PHYTOPLACENTA EXTRACT.

This extract operates through multiple pathways to enhance dermal well-being. It exerts anti-inflammatory effects by inhibiting nitric oxide (NO) production and suppressing cyclooxygenase-2 (COX-2) expression, both crucial inflammatory mediators. As a potent antioxidant, it neutralizes various free radicals including DPPH, superoxide anions, nitric oxide, and ABTS, thereby protecting skin from oxidative stress. Furthermore, specific components from *Potentilla chinensis* have been demonstrated to stimulate the synthesis of structural proteins like elastin and Type I collagen (COLIA1), while concurrently inhibiting matrix metallopeptidase-1 (MMP-1), an enzyme responsible for collagen degradation. The extract also enhances skin hydration by boosting aquaporin-3 synthesis, inhibits melanin production for a more luminous complexion, and contains active compounds such as potentilloside A, which mitigates cellular damage by inhibiting the phosphorylation of ERK, JNK, and c-Jun signaling pathways.