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Moumoujus

POTATO SH-OLIGOPEPTIDE-2.

Valuable / ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

POTATO SH-OLIGOPEPTIDE-2 is a cutting-edge synthetic polypeptide, identified as Insulin-like Growth Factor 1 (IGF-1), designed to function as a potent cellular signaling molecule. It significantly boosts skin regeneration, actively targeting multiple signs of aging by enhancing the production of vital skin components, and improving overall skin resilience and appearance.

Summary

Cell-communicating Wound healing Anti-aging Collagen boosting Elastin boosting Hydrating Skin barrier strengthening Regenerative

Science

Mechanism of Action

Operating as a biomimetic signaling molecule, SH-Oligopeptide-2 binds to specific cellular receptors on skin cells, initiating the crucial AKT pathway, which is integral to anti-aging processes, regeneration, and accelerated wound healing. This cascade of events stimulates fibroblast proliferation and the synthesis of essential extracellular matrix components, including collagen, elastin, and hyaluronic acid. Its action fosters active regeneration, supports the creation of new blood vessels, and enhances intercellular communication, collectively leading to a reduction in wrinkles, improved skin firmness, and superior hydration.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Stimulates collagen production, effectively reducing wrinkles, tightening skin, and improving overall appearance.
  2. 02 Strengthens the skin barrier and enhances communication between skin cells.
  3. 03 Increases the biosynthesis of Hyaluronic acid and other extracellular matrix components, leading to smoother, more youthful, and healthier skin while minimizing fine lines and deep wrinkles.
  4. 04 Promotes fibroblast proliferation and collagen synthesis, thereby enhancing skin elasticity and hydration.
  5. 05 General potato peptides have demonstrated in vitro ability to boost lipid metabolism in aged keratinocytes, suggesting a potential for recovering optimal lipid biosynthesis levels, which can improve skin barrier function and alleviate dehydration in aging skin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH for POTATO SH-OLIGOPEPTIDE-2's stability is not readily available. However, general potato proteins exhibit high interfacial stabilization in oil-in-water droplets near neutral pH (approximately 3-7). Aggregation for some potato protein fractions can occur around their isoelectric point, typically pH 5-6.

Safety

Safety Profile

CIR Status
Unknown
Sensitization risk Unknown

No specific CIR, SCCS, or FDA safety status is documented for POTATO SH-OLIGOPEPTIDE-2. However, SH-Oligopeptide-2 (Insulin-Like Growth Factor) is not currently found on EWG's Skin Deep Restricted or Unacceptable Lists. The 'POTATO' prefix refers to the recombinant source of the peptide, similar to other plant-derived peptides. The CIR Expert Panel has generally noted that Type I immediate hypersensitivity reactions could possibly occur following exposure to protein-derived ingredients, suggesting a need for careful assessment, although related sh-EGF is authorized in various cosmetic concentrations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

POTATO SH-OLIGOPEPTIDE-2 is a highly promising cellular regenerator that effectively targets multiple signs of aging by boosting essential skin components, positioning it as a valuable asset for advanced skincare formulations targeting comprehensive skin rejuvenation.

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