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POTASSIUM TYROSYL HISTIDINE OLIVAMIDE.

Valuable CAS - / ANTISTATIC, SKIN PROTECTING

POTASSIUM TYROSYL HISTIDINE OLIVAMIDE is an innovative complex ingredient, combining the amino acids tyrosine and histidine with an olive oil derivative. It is designed to support skin hydration, enhance barrier integrity, and potentially offer natural protection against environmental stressors.

Skin Protecting Antistatic Humectant Emollient Skin Conditioning UV Protection Support

Science

This sophisticated compound operates through several pathways. Its histidine component, a semi-essential amino acid, significantly contributes to the skin's Natural Moisturizing Factor (NMF) and functions as a protectant, aiding in barrier integrity. Histidine can also metabolize into urocanic acid (UCA), a natural sunscreen that absorbs UV radiation. The tyrosine element serves as a precursor for melanin, the skin's primary pigment, which forms in melanocytes to provide inherent UV defense. Additionally, the 'Olivamide' moiety, derived from olive oil, imparts notable emollient and conditioning benefits, further fortifying the skin's protective capacity. It also functions as an antistatic agent.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The histidine component of this ingredient features an imidazole group with a pKa value around 6.0, implying significant pH sensitivity. Its electrical charge and molecular interactions can undergo notable alterations within the pH range of 5.0 to 7.0. Furthermore, histidine phosphorylation is known to be labile at lower pH levels. This suggests that formulating at extreme pH values may compromise the stability or biological activity of the ingredient, particularly its histidine moiety. Being a potassium salt, it exhibits excellent water solubility.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While the comprehensive ingredient POTASSIUM TYROSYL HISTIDINE OLIVAMIDE has not undergone a direct safety review by bodies such as CIR or SCCS, its individual constituents—namely amino acids like histidine and derivatives from Olea europaea (olive)—have been subject to broader safety assessments by expert panels, including the CIR Expert Panel.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Given its multifaceted action in supporting hydration, barrier function, and potential UV protection pathways, POTASSIUM TYROSYL HISTIDINE OLIVAMIDE presents itself as a valuable multi-functional ingredient for advanced skincare formulations.


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