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Moumoujus

POTASSIUM SALICYLATE.

Valuable CAS 578-36-9 / ANTIMICROBIAL, PRESERVATIVE

Potassium Salicylate is a versatile ingredient prized for its anti-inflammatory, antimicrobial, and preservative capabilities in precision skincare formulations. Historically applied for conditions like melasma and as a sunscreen component, it contributes to overall skin health and product stability.

Summary

Anti-inflammatory Antimicrobial Preservative Cosmetic Biocide

Science

Mechanism of Action

This ingredient functions by inhibiting prostaglandin synthesis, thereby mitigating inflammatory mediators within the skin. Concurrently, its antimicrobial and biocide properties effectively control the proliferation of bacteria and fungi, preserving product integrity and promoting a healthier skin microbiome.

Research

Clinical Evidence

Medium confidence
Effective range 10–20%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Optimal stability and micro-biocidal efficacy for topical applications are observed within a pH range of 4.5 to 5.0, with an acceptable upper limit of 6.5. Formulations below pH 4.5 offer no enhanced benefits. Solutions with a pH above 7 are inherently unstable over extended periods in the presence of water. The ingredient is susceptible to pink discoloration upon light exposure, and solutions tend to darken under alkaline conditions.

Conflicts

  • Light exposure (induces pink discoloration)
  • Alkaline solutions (causes darkening)
  • Quinine compounds (forms indiffusible precipitates)
  • Citric acid (potential liberation and precipitation of salicylic acid)
  • Certain metals (may precipitate the anionic salt part)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Potassium Salicylate, along with other salicylates, safe for use when formulated to be non-irritating and non-sensitizing. Formulations should also aim to avoid increasing sun sensitivity, or include explicit instructions for daily sun protection if increased sensitivity is expected. While specific maximum concentrations for Potassium Salicylate were not detailed, the SCCS considers its parent compound, salicylic acid, safe up to 0.5% as a preservative, 3.0% for rinse-off hair products, and 2.0% for other product types, with restrictions for children under 3 years old (excluding shampoos).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Potassium Salicylate is a valuable multifunctional ingredient, offering effective anti-inflammatory and antimicrobial benefits while also serving as a crucial preservative for stable and safely formulated cosmetic products.

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