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POTASSIUM PALMITOYL HYDROLYZED WHEAT PROTEIN.

Valuable CAS 672298-01-0 / CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING

Potassium Palmitoyl Hydrolyzed Wheat Protein is a versatile ingredient derived from wheat protein, functioning as an emulsifier, cleanser, and conditioner for both skin and hair. It delivers beneficial amino acids that contribute to increased skin firmness, enhanced moisture retention, and overall suppleness, while actively supporting the skin's natural physiological balance.

Emulsifying Hair Conditioning Skin Conditioning Cleansing Film-forming Moisture retention pH balancing

Science

This ingredient operates by providing a rich source of amino acids from its hydrolyzed wheat protein component. On the skin, it exhibits excellent tensor and film-forming properties, which can visibly increase firmness and diminish the appearance of wrinkles. It also plays a crucial role in nourishing and softening the skin and hair, helping to retain essential moisture and regulate the skin's natural pH. Additionally, it serves as an effective emulsifier, assisting in the stabilization of cosmetic formulations.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Low molecular weight HWP (350 Da) demonstrated no significant dermal irritation or sensitization.

Transparency

Not commonly dusted

Information regarding 'dusting' characteristics and associated thresholds for this ingredient is not provided in the research data.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Wheat protein hydrolysates generally show enhanced stability in alkaline environments. They also contribute to improving the stability of other compounds within a formulation, particularly around a neutral pH of 6.8.


Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Hydrolyzed Wheat Protein is safe for use in cosmetics when stringent restrictions are observed. The ingredient must be formulated to contain peptides with a weight-average molecular weight of 3500 Da or less (equivalent to approximately 30 amino acids or 3.3 kDa). Furthermore, it should not be applied to damaged skin, used in products that may contact mucous membranes, or formulations with potential for incidental inhalation. This is crucial because while low molecular weight HWP (350 Da) is considered non-sensitizing, high molecular weight HWP (40,000-50,000 Da) has been associated with multiple reports of allergic reactions, including Type 1 immediate hypersensitivity. The SCCS also acknowledged reports of contact urticaria and anaphylaxis but, based on submitted data, found hydrolyzed wheat protein not to be an irritant to the skin. The FDA classifies peptones, including HWP, as Generally Recognized As Safe (GRAS) for direct food substance use.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Potassium Palmitoyl Hydrolyzed Wheat Protein is a valuable multifunctional ingredient, offering significant skin conditioning, firming, and moisturizing benefits, provided it adheres to the critical molecular weight safety restriction of 3500 Da or less to mitigate sensitization risk.


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