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POTASSIUM OCTOXYNOL-12 PHOSPHATE.

Valuable CAS - / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Potassium Octoxynol-12 Phosphate is a functional surfactant ingredient that excels as an emulsifying, cleansing, and solubilizing agent. It primarily works by reducing surface tension to stabilize formulations and facilitate the removal of oil and impurities.

Summary

emulsifying surfactant cleansing solubilizing

Science

Mechanism of Action

This ingredient functions by reducing the surface tension between different phases, particularly oil and water. This allows it to stabilize emulsions, facilitate the mixing of immiscible substances like oil and dirt with water for effective cleansing, and improve the dissolution of other ingredients within a solvent system, notably enhancing the water solubility of other surfactants.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical testing on a related compound, Octoxynol-9, at 1% concentration demonstrated non-irritancy in a 4-day patch test involving nine subjects.
  2. 02 Formulations containing 2% Octoxynol-9 were classified as ranging from moderately to minimally irritating in a 24-hour single-insult, occlusive patch test.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

It is instrumental in creating stable emulsions. During the synthesis of Octoxynols, careful purification is essential to limit potential trace impurities such as 1,4-dioxane, ethylene oxide, and unreacted C9 phenols.

Synergies

  • Other surfactants (for enhanced solubility)

Conflicts

  • strong oxidizing agents
  • strong reducing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
1.5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has consistently affirmed the safety of Potassium Octoxynol-12 Phosphate and Octoxynol-12 in both rinse-off and leave-on cosmetic products. In 2022, the highest reported concentration for Octoxynol-12 in leave-on face and neck products (non-spray) was 1.5%. The U.S. FDA also permits the use of Octoxynols as indirect food additives. Manufacturers are advised to employ robust purification methods to minimize impurities like 1,4-dioxane and heavy metals.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Potassium Octoxynol-12 Phosphate is a valuable surfactant, widely recognized for its safe use and crucial functional role in stabilizing emulsions, cleansing, and solubilizing other ingredients in cosmetic formulations.

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