Science
Mechanism of Action
This hydrolyzed collagen derivative functions by supplying free amino acids vital for the biosynthesis of collagen and elastin fibers within the dermis. Its oligopeptides precisely interact with fibroblast receptors, thereby upregulating the production of new collagen, elastin, and hyaluronic acid. This mechanism strengthens the skin's connective tissue, ensuring optimal elasticity and suppleness. Furthermore, it mimics naturally occurring polycollagen peptides to bolster skin repair, mitigating the appearance of lines and wrinkles and refining overall complexion and texture. The ingredient also provides moisturization, stimulates cell regeneration, reinforces the skin barrier, and offers protection against environmental stressors, ultimately increasing the diameter and cohesion of dermal collagen fibrils.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Hydrolyzed collagens or collagen peptides, within a concentration range of 50-500 μg/mL, have been shown to stimulate fibroblast activity in human and animal tissues without inducing toxicity.
- 02 Oral hydrolyzed collagen supplementation has demonstrated significant improvements in skin hydration and elasticity, alongside a reduction in wrinkle depth, observed over periods of 28 and 56 days.
- 03 Oral hydrolyzed collagen exhibits therapeutic and restorative capacities, diminishing fine and deep facial lines, and enhancing skin hydration and elasticity.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability and solubility are generally observed outside the hydrolyzed collagen's isoelectric point (pI), which typically ranges between 3.68 and 5.7. Collagen solutions maintain relatively stable viscoelasticity within a pH range of 6 to 10. As a protein fatty acid condensate, it can function as a detergent and foaming agent. While highly soluble in water, it requires co-formulation with other biopolymers to form films.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Panel determined Potassium Cocoyl Hydrolyzed Collagen and TEA-Cocoyl Hydrolyzed Collagen (related ingredients) to be safe as cosmetic ingredients, a conclusion reaffirmed in 2005. The CIR Panel decided in June 2024 to re-evaluate these related ingredients for potential sensitization and photosensitization. Potassium Myristoyl Hydrolyzed Collagen itself maintains a good safety profile, is considered non-toxic, and complies with international regulatory standards, including the European Union Cosmetics Regulation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Potassium Myristoyl Hydrolyzed Collagen is a valuable ingredient for promoting dermal regeneration, enhancing elasticity, and improving skin hydration across various skin types due to its well-understood mechanism and favorable safety profile.
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References
Sources