Science
Mechanism of Action
This extract functions through a rich array of bioactive compounds, including omega-3 fatty acids, vitamins (A, C, E, β-carotene), minerals, natural moisturizing factors (NMFs) like polysaccharides and amino acids, glutathione, carotenoids, coenzyme Q10, phenolic acids, and potent antioxidants. It neutralizes free radicals, safeguarding skin from oxidative stress, premature aging, and environmental damage. The extract also exhibits strong anti-inflammatory effects by reducing inflammatory mediators, which helps calm irritation and diminish redness. Its polysaccharides act as humectants, drawing and retaining moisture to enhance skin hydration. Furthermore, it supports wound healing and cellular repair by accelerating epidermal healing and stimulating cell proliferation, while omega-3 fatty acids and vitamin E fortify the skin barrier. It also offers anti-aging benefits by protecting against photoaging through miR-138-5p/Sirt1 signaling modulation and boosting collagen synthesis via its Vitamin C content. Its anti-inflammatory and non-comedogenic nature also supports acne management.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 In a 3-week face formulation use study, no irritation or dermal sensitization was observed, with dermatological changes in skin texture and acne remaining within expected ranges. A body lotion formulation also showed no dermal irritation or sensitization.
- 02 Face lotion and face treatment products containing this concentration were determined not to be sensitizing in maximization studies.
- 03 Demonstrated significant enhancement of cell growth in vitro over 72 hours, indicating regenerative potential.
- 04 Significantly increased cell viability and reduced oxidative damage and inflammation in UVB-induced cells in vitro, suggesting photoprotective and anti-inflammatory benefits. Note: cytotoxicity was observed at 4800 ng/mL (0.00048%).
Transparency
Dusting Analysis
Portulaca Oleracea Flower/Leaf/Stem Extract is unlikely to be commonly dusted. In vitro studies demonstrate significant biological activity, such as enhanced cell growth, at concentrations as low as 25 μg/mL (0.0025%). Reduced oxidative damage and inflammation were observed at concentrations as low as 150 ng/mL (0.000015%). The concentrations typically used in cosmetic products and tested in human safety studies (0.1% to 0.5%) are substantially higher than these effective in vitro thresholds, suggesting that formulations containing this ingredient at practical levels are likely to deliver active benefits.
The Formula
Formulation
Stability
This ingredient typically appears as a clear to pale yellow liquid, integrating seamlessly into formulations without contributing noticeable color or scent. It blends effectively with other ingredients.
Safety
Safety Profile
The CIR Expert Panel considers Portulaca oleracea-derived ingredients safe for cosmetic use when formulated to be non-sensitizing. The maximum verified concentration for non-spray face and neck products is 0.5%. However, a separate CIR report noted usage up to 0.008% in moisturizing leave-on dermal products. Formulators are advised to manage potentially sensitizing constituents, such as terpenes, and ensure good manufacturing practices to minimize impurities. A patch test is recommended for individual sensitivity. While Portulaca oleracea is listed in the US FDA Poisonous Plant Database concerning oxalate content and animal consumption, this is not directly relevant to its cosmetic safety at recommended concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Portulaca Oleracea Flower/Leaf/Stem Extract is a valuable ingredient offering a broad spectrum of benefits, including antioxidant protection, anti-inflammatory action, wound healing, and hydration, with a low risk of irritation across all skin types.
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