Science
Mechanism of Action
This extract functions through its rich profile of phytochemicals, including terpenoids, steroids, phenolic compounds, and flavonoids. It neutralizes free radicals by donating electrons, thereby exhibiting significant antioxidant activity. Furthermore, it possesses anti-inflammatory capabilities, helping to soothe stressed skin. Its contribution to wound healing involves stimulating epidermal closure, promoting re-epithelization, and enhancing granulation tissue formation.
Research
Clinical Evidence
Low confidence0.01%
Key findings
- 01 An n-hexane extract of Portulaca grandiflora, when applied at a concentration of 100 µg/ml (equivalent to 0.01%), significantly enhanced wound healing through increased cell migration and accelerated wound closure.
Transparency
Dusting Analysis
While precise dusting thresholds are not specified, the only clinical efficacy data available is from an in vitro study at a relatively low concentration of 0.01%. This suggests that high concentrations are not currently supported by robust efficacy data, thus 'dusting' concerns are less relevant for this ingredient based on current research.
The Formula
Formulation
Stability
The extract's solubility varies significantly based on the extraction solvent used, indicating a diverse array of compounds with different properties. Water-soluble extractives constitute approximately 2.7%, while ethanol-soluble components are considerably higher at 18.6%.
Safety
Safety Profile
EWG Skin Deep assesses Portulaca Grandiflora Extract with a 'LOW' hazard rating for Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity. However, it is noted that EWG VERIFIED products require adequate substantiation for its inclusion. Paula's Choice generally considers this ingredient to be non-irritating.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Portulaca Grandiflora Extract presents promising in vitro data for wound healing, antioxidant, and anti-inflammatory benefits, with low safety concerns, making it a valuable optional addition to formulations aimed at soothing and supporting skin repair, though further human clinical trials are needed for broader efficacy claims.
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