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PORPHYRIDIUM CRUENTUM CULTURE CONDITIONED MEDIA.

Valuable CAS - / ANTIOXIDANT

Porphyridium Cruentum Culture Conditioned Media is a marine-derived powerhouse, rich in components like phycoerythrin and exopolysaccharides, designed to extensively revitalize skin. It acts as a comprehensive hydrator, protector, and rejuvenator, addressing concerns from visible damage and redness to fine lines and environmental stress.

Summary

Antioxidant Moisturizing Anti-inflammatory Skin Barrier Support Anti-aging Redness Reduction Circulation Boosting Collagen Boosting Cell Regeneration UV Protection

Science

Mechanism of Action

This ingredient operates through a multifaceted biological pathway to enhance skin vitality. It notably improves the skin's natural oxygenation and stimulates micro-circulation, which collectively soothe visible damage and diminish redness. By fostering hyaluronic acid production, it effectively moisturizes, decongests, and helps reduce the appearance of wrinkles and fine lines. Its exopolysaccharides boost skin's resilience, elasticity, and hydration, concurrently enhancing the skin barrier and promoting wound healing through the upregulation of key genes such as AQP3, FLG, IVL, LOR, ELN, and FBN1. Functioning as a potent antioxidant, it defends against oxidative stress, neutralizes free radicals, and reduces intracellular Reactive Oxygen Species (ROS). A significant active component, phycoerythrin, offers robust protection against UVA irradiation, premature aging, and sun damage, while stimulating cellular regeneration and bolstering collagen synthesis crucial for maintaining skin elasticity and firmness.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A Human Repeated Insult Patch Test (HRIPT) involving 107 subjects confirmed a moisturizer formulation containing 0.000545% Porphyridium Cruentum Extract was non-irritating and non-sensitizing.
  2. 02 Research indicated that purified phycoerythrin, a component from P. cruentum culture at 10 nM concentration, provided protection to cells from UVA irradiation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient enhances overall product stability by preventing oxidative degradation, thereby extending the longevity of the formulation.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The CIR Panel issued a tentative report in March 2021, indicating insufficient systemic toxicity data to fully determine safety for Porphyridium Cruentum Culture Conditioned Media and related red algae ingredients. However, multiple Human Repeated Insult Patch Tests (HRIPT) for Porphyridium Cruentum Extract (at 0.000545% in a formulation) and 'Porphyridium Conditioned Media (PCM)' consistently confirmed it as hypoallergenic, non-irritating, and safe for sensitive skin, addressing topical safety concerns.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Porphyridium Cruentum Culture Conditioned Media is a valuable, multi-functional ingredient demonstrating robust benefits in hydration, anti-aging, antioxidant defense, and soothing, supported by positive topical safety data, though further systemic toxicity data are still desired by the CIR.

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