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PORPHOBILINOGEN LACTAM.

Insufficient Data CAS 3468-98-2 / SKIN CONDITIONING

Porphobilinogen Lactam is an ingredient identified for its potential skin conditioning properties. While its precise mechanism and benefits within topical skincare formulations are currently not extensively documented, it is suggested to contribute to the skin's overall feel and appearance.

Skin Conditioning

Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.5 – 8
0 7 14

Stability

Chemical synthesis indicates that Porphobilinogen Lactam is insoluble in warm dilute acid. Processing data suggests stability within the pH range of approximately 4.5 to 8, with crystallization occurring around pH 4.5, and its ethyl ester handled in solutions up to pH 8.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Specific cosmetic ingredient safety data for Porphobilinogen Lactam (CIR, SCCS, FDA status) is currently unavailable. It is important to note that the parent compound, Porphobilinogen, a natural intermediate in heme biosynthesis, can act as a phototoxin, neurotoxin, and metabotoxin at chronically high systemic levels, and is a biomarker for porphyria. The safety profile of the lactam form in topical applications requires further dedicated investigation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Due to a significant lack of specific cosmetic safety assessments, clinical efficacy data, and established mechanisms of action for Porphobilinogen Lactam, its utility in skincare formulations cannot be definitively evaluated at this time.


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