Science
Mechanism of Action
As a polyurethane polymer, POLYURETHANE-82 contributes to skin integrity by forming a flexible, non-occlusive film that helps to minimize transepidermal water loss, thereby maintaining optimal hydration. Beyond this crucial barrier function, the broader class of modified polyurethanes has demonstrated a capacity to modulate inflammatory responses and promote tissue healing, suggesting a role in advanced skin recovery and conditioning.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
POLYURETHANE-82 exhibits low water solubility. Polyurethanes generally demonstrate significant hydrolytic stability within a broad pH range of 4.0 to 9.0. However, the precise stability characteristics can vary based on the polymer's specific chemical composition (e.g., polyester- or polyether-based), which may influence its degradation profile and impact the surrounding formulation's pH.
Conflicts
- Acetone
- Ketones (e.g., Methyl Ethyl Ketone, Cyclohexanone)
- Strong acids (e.g., Sulfuric Acid 98%)
- Strong bases (e.g., Ammonium Hydroxide, Sodium Hydroxide 50% can cause significant degradation)
- Benzene
- Aniline
- Carbon Disulfide
- Chloroform
- Dichloromethane
- Nitrobenzene
- Phenol
- Tetrachloroethylene
- Tetrahydrofuran
- Toluene
- 1,1,1-Trichloroethane
- Trichloroethylene
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed 66 polyurethane ingredients, concluding their safety under current practices of use and concentration, provided they are formulated to be non-sensitizing. The Panel confirmed no detectable residual isocyanates or other monomers. Formulators should be aware that polyurethane raw materials may be supplied in emulsions or solutions containing potential sensitizers, such as methylisothiazolinone (MI), and should avoid their accumulation to significant concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYURETHANE-82 is a valuable polymeric ingredient for skincare formulations, offering effective film-forming and moisture retention capabilities with a favorable safety profile.
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