Science
Mechanism of Action
This ingredient operates by forming an imperceptible, cohesive film across the skin's surface, establishing a protective barrier. This film exhibits strong adhesion, working to mitigate damage from external factors such as chemical exposure, UV radiation, and environmental pollutants. Additionally, it confers moisturizing properties, leading to a reduction in skin roughness and an enhancement in the skin's softness and elasticity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In a study involving a 9.6% concentration of Polyurethane-14 dissolved in 55% ethanol, mild to moderate irritation, characterized by erythema and papules, was observed in a limited number of subjects. However, these observations did not significantly differ from the effects seen with the ethanol control. Furthermore, inhalation studies in rats revealed no toxicologically significant clinical findings.
Transparency
Dusting Analysis
The provided research data does not contain information regarding Polyurethane-14 being commonly 'dusted' or any associated dusting thresholds.
The Formula
Formulation
Stability
Polyurethane-14 is anticipated to maintain stability without significant hydrolysis within a pH range of 4.0 to 9.0. Instability may occur under strongly acidic conditions (pH 1.0-3.0), where amide groups can undergo hydrolysis. The ingredient is reported to be stable for 3 years when stored between 5°C and 50°C.
Conflicts
- Requires careful formulation to ensure it is non-sensitizing, particularly when incorporated into solutions containing other known sensitizers (e.g., methylisothiazolinone).
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that polyurethanes, including Polyurethane-14, are safe for use under current practices and concentrations, provided the final formulation is non-sensitizing. The panel also determined that there would be no detectable residual isocyanate or other monomer impurities. Concentrations up to 9% are reported in cosmetic applications, including dermal preparations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyurethane-14 is a valuable film-forming agent, offering robust environmental protection and moisturizing benefits across all skin types, with a low irritancy profile when correctly formulated.
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References
Sources