Science
Mechanism of Action
POLYURETHANE-100 operates primarily as a film-forming agent, depositing a resilient, continuous polymeric layer on the skin's surface. This mechanism provides integral flexibility and long-lasting properties to formulations, improving durability and water resistance. Additionally, it functions as a skin conditioning agent, actively contributing to the maintenance of healthy skin. By forming an occlusive barrier, it aids in moisturization, imparting softness and elasticity while offering protection from external environmental factors such as solar radiation, cold temperatures, and pollution.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 An in vitro study utilizing human keratinocyte (HaCaT) cell assays indicated that polyurethane foam extracts were non-toxic at concentrations up to 6.25% (IC0). Cytotoxicity was observed to increase notably above 25%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While a specific optimal pH range for POLYURETHANE-100's stability in cosmetic applications is not explicitly defined, polyurethane-based dispersions are commonly water-based. General polyurethane materials exhibit varying chemical resistance, with severe effects noted upon exposure to substances like carbon tetrachloride and aluminum chloride.
Conflicts
- High concentrations of sensitizers when combined with other ingredients delivered in emulsions or solutions
- Carbon Tetrachloride (general polyurethane incompatibility)
- Aluminum Chloride (general polyurethane incompatibility)
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has evaluated the safety of 66 polyurethane ingredients, concluding their safety in current cosmetic practices and concentrations, provided they are formulated to be non-sensitizing and contain no detectable residual isocyanates or other monomers. Formulators are advised to consider potential sensitizers, such as methylisothiazolinone, present in accompanying emulsions or solutions. The U.S. Food and Drug Administration (FDA) regulates its use, necessitating adherence to rigorous safety standards.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable film-forming polymer that enhances product durability and offers comprehensive skin conditioning and protection, characterized by a favorable safety profile and broad skin compatibility.
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