Science
Mechanism of Action
As a cationic polymer, Polyquaternium-80 electrostatically adheres to the negatively charged surface of the skin. This ionic interaction facilitates its role in providing hydration and conditioning benefits. Furthermore, it functions as an emulsifying surfactant, stabilizing oil and water components in formulations, and contributes antibacterial activity to extend product shelf life.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyquaternium-80 maintains stability within its optimal pH range of 6.5 to 8.5.
Safety
Safety Profile
While a specific Cosmetic Ingredient Review (CIR) for Polyquaternium-80 is not available, other polyquaternium variants have been reviewed and deemed safe at various concentrations (e.g., Polyquaternium-22 up to 2%, Polyquaternium-39 up to 3%). SkinSAFE categorizes Polyquaternium-80 as 'Teen SAFE', 'Baby SAFE', 'Irritant Free', 'Fragrance Free', 'Paraben Free', and 'Dye Free'. The Environmental Working Group (EWG) assesses its risk as 'LOW' for cancer and developmental/reproductive toxicity, and 'LOW_MODERATE' for allergies and immunotoxicity, suggesting an overall profile of negligible adverse effects. The New Zealand EPA Inventory notes its use under appropriate group standards rather than individual approval.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyquaternium-80 is a valuable multifunctional ingredient, enhancing skin conditioning, formulation stability, and offering broad compatibility across all skin types with a generally low safety risk.
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