Science
Mechanism of Action
As a cationic polymer, Polyquaternium-78 possesses positively charged groups that establish ionic bonds with the inherently negatively charged surface of the skin. This interaction is fundamental to its conditioning capabilities, fostering improvements in skin's tactile qualities, specifically softness and smoothness. Furthermore, it functions as an effective film-former, depositing a lightweight, protective layer on the epidermis. This barrier is instrumental in minimizing transepidermal water loss and safeguarding the skin from external irritants, thus promoting a well-conditioned complexion.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyquaternium-78 can be effectively processed using both hot and cold methods. For optimal shelf life, products containing this ingredient should be stored in sealed containers at temperatures not exceeding 49°C (120°F) for up to 24 months.
Safety
Safety Profile
While Polyquaternium-78 has not undergone individual review by the Cosmetic Ingredient Review (CIR), related Polyquaternium ingredients have been deemed safe. Extensive safety testing on human volunteers, including a 48-hour occlusive skin patch test on 53 subjects, showed no visible skin reactions or potential for dermal irritation. Repeat Insult Patch Testing (HRIPT) further affirmed its mildness, demonstrating no potential for dermal irritation or allergic contact sensitization, even for ocular exposure in formulations. It is recognized as 'Irritant Free' by SkinSAFE.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyquaternium-78 is a valuable conditioning and barrier-supporting polymer, demonstrating broad skin compatibility and a low risk of irritation and sensitization across all skin types.
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