Science
Mechanism of Action
As a cationic polymer, Polyquaternium-73 operates by neutralizing electrical charges on the skin surface, imparting antistatic properties. It exhibits strong antibacterial efficacy, particularly against *Propionibacterium acnes*, contributing to its significant anti-acne effects. The ingredient forms a protective film on the skin, which aids in conditioning and moisture retention, and its mechanism also includes potent inhibition of melanin production, leading to brightening effects. Additionally, it possesses foaming properties, useful in cleansing formulations.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Demonstrated a minimum inhibitory concentration (MIC) against *Propionibacterium acnes*, and reduced acne rash by 50% within two weeks of use.
- 02 Suppressed melanin formation by 50% at 0.000003% and 83% at 0.00001%. At 0.1 ppm (equivalent to 0.00001%), it completely inhibited melanin formation, outperforming kojic acid.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyquaternium-73 is stable within a pH range of 5.5 to 8.0 and demonstrates good thermal stability up to 90°C. It exhibits slight solubility in water (0.6068 mg/L @ 25°C est) but is soluble in various organic solvents including butylene glycol, propylene glycol, ethanol, and 1,2-pentanediol. For optimal integration, it is recommended to pre-dissolve it in one of these organic solvents. Due to its photostability characteristics, products containing Polyquaternium-73 should be stored in opaque containers to maintain ingredient integrity.
Synergies
- Conditioning agents
- Surfactants
- Preservatives
Safety
Safety Profile
Polyquaternium-73 is deemed highly safe and non-irritant for cosmetic use, as determined by the Cosmetic Ingredient Review (CIR), provided it adheres to a maximum concentration of 0.002%. Tests indicate no eye irritation, skin irritation, sensitization, or photosensitization.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyquaternium-73 is a valuable, multi-functional ingredient demonstrating potent anti-acne and brightening effects at extremely low concentrations, while offering excellent skin conditioning with a high safety profile suitable for all skin types.
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