Science
Mechanism of Action
As a positively charged synthetic polymer, POLYQUATERNIUM-28 electrostatically binds to the naturally negatively charged skin surface. This interaction forms a clear, flexible, and tack-free film, which delivers mild conditioning and moisturizing effects. The film also acts as a physical barrier, effectively minimizing transepidermal water loss and offering protection against external irritants. Additionally, it exhibits humectant properties, drawing moisture from the surrounding environment to the skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
While excessive use may lead to product buildup, this is primarily a formulation/aesthetic concern rather than a 'dusting' related to irritation or topical toxicity.
The Formula
Formulation
Stability
POLYQUATERNIUM-28 demonstrates high water solubility and robust stability against hydrolysis across a broad pH spectrum, ranging from 3 to 12. It forms transparent, flexible films that provide good lubricity. However, formulating with excessive amounts may lead to perceptible product buildup on the skin.
Synergies
- Nonionic surfactants
- Amphoteric surfactants
- Anionic surfactants
Safety
Safety Profile
Evaluated by the Cosmetic Ingredient Review (CIR) Expert Panel, POLYQUATERNIUM-28 is deemed safe for use in cosmetic applications as directed, presenting a low risk of topical toxicity. While a specific maximum concentration for POLYQUATERNIUM-28 was not identified, related polyquaternium compounds, such as Polyquaternium-11, have been clinically tested at concentrations up to 50% without inducing sensitization, with only isolated instances of transient irritation observed.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYQUATERNIUM-28 is a valuable ingredient for enhancing skin conditioning, barrier integrity, and sensory texture through its film-forming and moisturizing capabilities, with a favorable safety profile.
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