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Moumoujus

POLYQUATERNIUM-111.

Valuable CAS 67990-40-3 / ANTISTATIC, HAIR CONDITIONING

POLYQUATERNIUM-111 is a cationic film-forming polymer engineered to enhance skin texture and hydration. It creates a flexible, transparent barrier on the skin's surface, effectively minimizing moisture loss and improving overall conditioning.

Summary

Film forming Humectant Skin conditioning Antistatic Barrier support

Science

Mechanism of Action

This ingredient functions as a cationic film-forming polymer, depositing a continuous, non-sticky, and flexible film on the skin. It acts as a humectant, actively attracting and binding moisture to the skin to boost hydration and alleviate dryness. By forming a protective barrier, POLYQUATERNIUM-111 helps to reduce transepidermal water loss and shield the skin from environmental stressors, contributing to a smoother, softer, and more conditioned feel.

Research

Clinical Evidence

High confidence
Effective range 0.3–50%
Optimal

N/A

Key findings

  1. 01 Product formulations containing POLYQUATERNIUM-111 at 2.0% demonstrated no irritation in clinical settings. Even at 0.3% in a product formulation, irritation was only mild.
  2. 02 The ingredient, as a raw material, at concentrations up to 50% in water, showed no signs of skin or eye irritation in animal tests.
  3. 03 Human repeated insult patch tests at concentrations up to 50% indicated no sensitization potential and only isolated, transient instances of skin irritation.
  4. 04 A single insult patch test with 9.5% POLYQUATERNIUM-111 in water resulted in slight skin irritation in only 1 out of 19 subjects over 24 hours.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

POLYQUATERNIUM-111 exhibits resilience to heat. While its cationic charge remains stable across pH ranges, excessively high pH levels may diminish its water solubility due to the presence of hydroxyl groups. A 10% solution typically maintains a pH between 5.0 and 7.0.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
50%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has consistently affirmed POLYQUATERNIUM-111 as safe for cosmetic use, reaffirming this conclusion in 2003 and 2023. It is generally recognized as mild, non-irritating, and non-sensitizing to the skin. Clinical and animal studies support its low irritation and sensitization potential, even at high concentrations. It complies with the general provisions for cosmetic ingredients in the European Union.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

POLYQUATERNIUM-111 is a valuable multi-functional ingredient, offering significant skin conditioning, hydration, and barrier support with a robust safety profile across various skin types.

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