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Moumoujus

POLYPERFLUOROMETHYLISOPROPYL ETHER.

Avoid CAS 69991-67-9 / SKIN CONDITIONING

Polyperfluoromethylisopropyl Ether is a synthetic fluorinated ether, characterized by its molecular composition of carbon, fluorine, and oxygen. This compound is notably lightweight, highly stable, and exceptionally hydrophobic, contributing to a smooth skin feel and enhancing product longevity.

Summary

Skin conditioning Protective barrier formation Moisture retention Texture enhancement Water-repellent Oil-resistant Smoothing agent

Science

Mechanism of Action

This ingredient functions by forming a soft, imperceptible, hydrophobic film on the skin's surface. This protective layer repels water and effectively minimizes moisture loss, thereby aiding in the preservation of the skin's natural hydration balance. Beyond its skin-conditioning benefits, it refines the sensory profile of cosmetic formulations, delivering a comfortable, silky feel without imparting a greasy residue. As a fluoropolymer, it also provides enhanced water- and oil-resistance, contributing to the extended wear and durability of cosmetic products.

Research

Clinical Evidence

Low confidence
Effective range 0.05–3%
Optimal

N/A

Key findings

  1. 01 Balan, Bruton et al. (2024) publication referenced by FDA.

Transparency

Dusting Analysis

Not commonly dusted

As a synthetic fluorinated ether oil, this ingredient is not typically associated with dusting concerns in cosmetic formulations.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient demonstrates exceptional chemical stability, maintaining its efficacy even under extreme conditions. It does not readily interact with other components, thereby enhancing the overall durability and longevity of cosmetic formulations.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

Polyperfluoromethylisopropyl Ether is classified as a Per- and Polyfluoroalkyl Substance (PFAS). The FDA's 2025 report indicated significant data gaps for this ingredient, precluding a 'low safety concern' determination, despite initial data suggesting a low potential for toxicity. Key missing information includes comprehensive data on use levels, dermal/oral absorption, and dermal toxicity. While generally considered to rarely cause allergic reactions or skin irritation, PFAS as a class are known as 'forever chemicals' due to their environmental persistence and bioaccumulation in the human body. Associated concerns include potential effects on thyroid, liver, nervous, reproductive, and immune systems, as well as carcinogenicity and endocrine disruption. The Environmental Working Group (EWG) deems this ingredient unacceptable for EWG VERIFIED products due to its PFAS classification and related concerns.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Despite its functional benefits in cosmetic formulations such as skin conditioning and enhanced product durability, Polyperfluoromethylisopropyl Ether is classified as a PFAS 'forever chemical' with substantial safety data gaps and known environmental persistence concerns, rendering it an ingredient to avoid.

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