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POLYPEPTIDE-23.

Insufficient Data CAS - / SKIN CONDITIONING

Polypeptide-23 is a synthetic peptide engineered for its skin conditioning capabilities. It functions as a cellular messenger, theoretically signaling skin cells to enhance the production of vital structural proteins like collagen and elastin. This action is believed to contribute to improved skin elasticity, hydration, and overall skin health, with its current applications primarily focused on lash and brow enhancement.

Skin conditioning Collagen synthesis support Elastin synthesis support Barrier function improvement Anti-aging Hydration

Science

As a biomimetic messenger, Polypeptide-23 is hypothesized to interact with skin cells, stimulating intracellular pathways that lead to increased synthesis of essential proteins, specifically collagen and elastin. This cascade of activity is intended to fortify the skin's structural integrity, potentially resulting in enhanced barrier function, improved dermal elasticity, a reduction in the appearance of fine lines and wrinkles, and a boost in overall skin hydration and plumpness.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Peptides, being proteinaceous, can experience a loss of biological activity when exposed to significant pH variations. Therefore, maintaining precise pH control, typically within the 4.5-6.5 range, is generally crucial for preserving product stability and ensuring the efficacy of such ingredients in skincare formulations.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments for Polypeptide-23 by prominent regulatory bodies such as the CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) are currently unavailable. While general safety evaluations for broader peptide categories have indicated their safe use, specific hazard identification, GHS classification, and toxicity data (oral, dermal, inhalation) for Polypeptide-23 are reported as 'not determined' in public sources, indicating a lack of comprehensive, ingredient-specific safety profiling. Individual cosmetic ingredients are not subject to pre-market approval by the FDA.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

The available research provides a theoretical mechanism of action for Polypeptide-23 but lacks specific clinical studies, optimal concentration data, and comprehensive, ingredient-specific safety assessments necessary to fully evaluate its broader efficacy and safety for general skincare applications.


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