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Moumoujus

POLYGONUM FAGOPYRUM LEAF EXTRACT.

Valuable CAS 89958-09-8 / SKIN CONDITIONING

Polygonum Fagopyrum Leaf Extract, derived from buckwheat leaves, is a multifaceted botanical ingredient that delivers comprehensive protective and rejuvenating benefits to the skin. It acts as a potent antioxidant, safeguarding against environmental stressors, while also providing anti-inflammatory effects to calm irritation and redness. Furthermore, this extract supports skin hydration, enhances barrier integrity, and exhibits potential for improving skin elasticity and evening skin tone, making it adaptable for diverse skincare formulations.

Summary

Antioxidant Anti-inflammatory Moisturizing Skin Elasticity Enhancer Skin Firming Skin Brightening Anti-Wrinkle Skin Barrier Support UV Protection

Science

Mechanism of Action

This extract primarily exerts its effects through robust antioxidant activity, effectively neutralizing free radicals to reduce oxidative damage and protect cellular membranes, particularly those exposed to UV radiation. Its inherent anti-inflammatory properties contribute to soothing irritated skin and diminishing redness. The flavonoids present, such as rutin, quercetin, and vitexin, are postulated to enhance skin elasticity and firmness. Functioning as a humectant, it draws moisture into the skin, thereby improving hydration. Additionally, studies suggest its potential to inhibit tyrosinase, which could lead to skin brightening, and elastase, offering anti-wrinkle advantages. These combined actions collectively fortify the skin barrier and offer defense against external aggressors like pollution and UV rays.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An ethyl acetate fraction of Fagopyrum esculentum extracts demonstrated a prominent cellular protective effect, particularly against photohemolysis in human erythrocytes, at a concentration of 10 µg/mL in *in vitro* models.
  2. 02 Aglycone fractions, derived specifically from the hull and dehulled seeds of Fagopyrum esculentum, exhibited *in vitro* inhibitory effects on both tyrosinase and elastase enzymes, suggesting potential for skin brightening and anti-wrinkle applications. It is important to note that a 50% ethanol extract showed negligible inhibitory activity in these assays.
  3. 03 Fagopyrum esculentum extract displayed strong *in vitro* antioxidant activity, achieving an 81.64% reduction in DPPH radicals at a concentration of 1 mg/ml, confirming its concentration-dependent free radical scavenging capacity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Due to the presence of phototoxic fagopyrins, product formulations containing this extract should be protected from light exposure to maintain stability and prevent potential issues.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically reviewed Polygonum Fagopyrum Leaf Extract. While generally well-tolerated and rated with low concern for allergies and immunotoxicity by EWG Skin Deep, individuals with extremely sensitive skin or a known allergy to buckwheat should exercise caution. Buckwheat leaves contain phototoxic fagopyrins (ranging from 0.3–2.3 mg/g), which in cases of very high consumption or exposure to potent extracts, could induce 'fagopyrism'—a photosensitive skin inflammation. The European Union has approved the use of buckwheat seed extract in cosmetic applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Polygonum Fagopyrum Leaf Extract is a valuable ingredient, offering broad-spectrum antioxidant protection, anti-inflammatory benefits, and potential for improving skin elasticity and tone, though its phototoxic components necessitate careful formulation.

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