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POLYGLYCERYL-5 ISOSTEARATE.

Valuable CAS - / SURFACTANT - EMULSIFYING

Polyglyceryl-5 Isostearate is a versatile nonionic emulsifier critical for creating stable and uniform oil-in-water and water-in-oil emulsions in cosmetic formulations. Beyond its functional role in blending immiscible phases, it actively conditions the skin, contributing to improved hydration and texture.

Summary

emulsifying skin conditioning emollient

Science

Mechanism of Action

This ingredient primarily functions as an emulsifier by significantly lowering the interfacial tension between oil and water phases, thereby facilitating the creation and stabilization of homogenous cosmetic emulsions. On the skin, it serves as a conditioning agent, enhancing moisture retention, softening the skin's texture, and improving overall skin feel. It also contributes to desirable product spreadability and sensory characteristics.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

As an amphiphilic compound, Polyglyceryl-5 Isostearate effectively stabilizes both oil-in-water (O/W) and water-in-oil (W/O) emulsions. Related polyglyceryl esters demonstrate stability across a broad pH range, typically from 3 to 9. It exhibits excellent compatibility with diverse oils, including vegetable oils, esters, mineral oil, and silicones, and shows good tolerance to electrolytes, with related compounds tolerating up to 3% NaCl or divalent salts. Its capacity to generate liquid crystal structures further enhances overall formulation stability.

Safety

Safety Profile

CIR Status
Safe as used with restrictions
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Polyglyceryl-5 Isostearate alongside 274 other polyglyceryl fatty acid esters, concluding they are safe for use in cosmetics within current practices and concentrations, provided they are formulated to be non-irritating. While polyglycerol esters generally do not cause adverse effects, related Polyglyceryl-2 Isostearate elicited slight irritation at 7%. Related ingredients like Glyceryl Isostearate are approved by regulatory bodies such as the FDA and EU Cosmetic Regulation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

As a low-irritancy, low-comedogenicity emulsifier and skin conditioner with broad compatibility and a favorable safety profile, Polyglyceryl-5 Isostearate is a valuable ingredient for stable and cosmetically elegant formulations across all skin types.

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